Usnic Acid
Usnic Acid is extracted from Usnea diffracta Vain or Usnea longissima Ach. Stanford Chemicals has been providing quality Usnic Acid and many other natural plant extract for over 15 years.
Product Name | Usnic Acid |
CAS No. | 125-46-2 |
Molecular Formula | C18H16O7 |
Molecular Weight | 344.32 |
Botanical Source | Usnea diffracta Vain or Usnea longissima Ach |
Purity | 98% HPLC |
Appearance | Yellow powder |
Package | 25 kg/drum |
Storage | Stored in cool & dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Usnic Acid Safety Tips
Handling of Usnic Acid should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Products
-
Lichen Usnea Extract, Specification: 98% Usnic acid (Sodium) HPLC. Botanical Source: Lichen Usnea.
References
- 1. Proton-shuttling lichen compound usnic Acid affects mitochondrial and lysosomal function in cancer cells.
Bessadottir M, Egilsson M, Einarsdottir E, Magnusdottir IH, Ogmundsdottir MH, Omarsdottir S, Ogmundsdottir HM.PLoS One. 2012;7(12):e51296. doi: 10.1371/journal.pone.0051296. Epub 2012 Dec 5.
- 2. Biological Activities of Toninia candida and Usnea barbata Together with Their Norstictic Acid and Usnic Acid Constituents.
Rankovi? B, Kosani? M, Stanojkovi? T, Vasiljevi? P, Manojlovi? N.Int J Mol Sci. 2012 Nov 12;13(11):14707-22. doi: 10.3390/ijms131114707.
- 3. Review article: herbal and dietary supplement hepatotoxicity.
Bunchorntavakul C, Reddy KR.Aliment Pharmacol Ther. 2013 Jan;37(1):3-17. doi: 10.1111/apt.12109. Epub 2012 Nov 5.
- 4. Anti-viral activity of (-)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009.
Sokolov DN, Zarubaev VV, Shtro AA, Polovinka MP, Luzina OA, Komarova NI, Salakhutdinov NF, Kiselev OI.Bioorg Med Chem Lett. 2012 Dec 1;22(23):7060-4. doi: 10.1016/j.bmcl.2012.09.084. Epub 2012 Oct 4.
- 5. Membrane-damaging potential of natural L-(-)-usnic acid in Staphylococcus aureus.
Gupta VK, Verma S, Gupta S, Singh A, Pal A, Srivastava SK, Srivastava PK, Singh SC, Darokar MP.Eur J Clin Microbiol Infect Dis. 2012 Dec;31(12):3375-83. doi: 10.1007/s10096-012-1706-7. Epub 2012 Aug 3.
- 6. Interactive toxicity of usnic acid and lipopolysaccharides in human liver HepG2 cells.
Sahu SC, O'Donnell MW Jr, Sprando RL.J Appl Toxicol. 2012 Sep;32(9):739-49. doi: 10.1002/jat.2768. Epub 2012 Jul 9.
- 7. Antioxidative and cardiovascular-protective activities of metabolite usnic acid and psoromic acid produced by lichen species Usnea complanata under submerged fermentation.
Behera BC, Mahadik N, Morey M.Pharm Biol. 2012 Aug;50(8):968-79. doi: 10.3109/13880209.2012.654396.
- 8. Proteomic study on usnic-acid-induced hepatotoxicity in rats.
Liu Q, Zhao X, Lu X, Fan X, Wang Y.J Agric Food Chem. 2012 Jul 25;60(29):7312-7. doi: 10.1021/jf2046834. Epub 2012 Jul 16.
- 9. Influence of usnic acid and its derivatives on the activity of mammalian poly(ADP-ribose)polymerase 1 and DNA polymerase β.
Zakharenko A, Sokolov D, Luzina O, Sukhanova M, Khodyreva S, Zakharova O, Salakhutdinov N, Lavrik O.Med Chem. 2012 Sep;8(5):883-93.
- 10. Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.
Song Y, Dai F, Zhai D, Dong Y, Zhang J, Lu B, Luo J, Liu M, Yi Z.Angiogenesis. 2012 Sep;15(3):421-32. doi: 10.1007/s10456-012-9270-4. Epub 2012 Apr 11.
- 11. Cytotoxic Activity and Antioxidant Capacity of Purified Lichen Metabolites: An In Vitro Study.
Brisdelli F, Perilli M, Sellitri D, Piovano M, Garbarino JA, Nicoletti M, Bozzi A, Amicosante G, Celenza G.Phytother Res. 2012 May 25. doi: 10.1002/ptr.4739. [Epub ahead of print]
- 12. Studies on nutritional requirement for the culture of lichen Ramalina nervulosa and Ramalina pacifica to enhance the production of antioxidant metabolites.
Verma N, Behera BC, Joshi A.Folia Microbiol (Praha). 2012 Mar;57(2):107-14. doi: 10.1007/s12223-012-0100-2. Epub 2012 Feb 22.
- 13. Lichen secondary metabolites are responsible for induction of apoptosis in HT-29 and A2780 human cancer cell lines.
Ba?korová M, Jend?elovský R, Kello M, Ba?kor M, Mikeš J, Fedoro?ko P.Toxicol In Vitro. 2012 Apr;26(3):462-8. doi: 10.1016/j.tiv.2012.01.017. Epub 2012 Jan 21.
- 14. Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y).
Rabelo TK, Zeidán-Chuliá F, Vasques LM, dos Santos JP, da Rocha RF, Pasquali MA, Rybarczyk-Filho JL, Araújo AA, Moreira JC, Gelain DP.Toxicol In Vitro. 2012 Mar;26(2):304-14. doi: 10.1016/j.tiv.2011.12.003. Epub 2011 Dec 13.
- 15. Inhibitory activity of Fe(3) O(4)/oleic acid/usnic acid-core/shell/extra-shell nanofluid on S. aureus biofilm development.
Grumezescu AM, Saviuc C, Chifiriuc MC, Hristu R, Mihaiescu DE, Balaure P, Stanciu G, Lazar V.IEEE Trans Nanobioscience. 2011 Dec;10(4):269-74. doi: 10.1109/TNB.2011.2178263. Epub 2011 Dec 7.
- 16. In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods.
Segatore B, Bellio P, Setacci D, Brisdelli F, Piovano M, Garbarino JA, Nicoletti M, Amicosante G, Perilli M, Celenza G.Phytomedicine. 2012 Feb 15;19(3-4):341-7. doi: 10.1016/j.phymed.2011.10.012. Epub 2011 Nov 25.
- 17. A new depsidone and antibacterial activities of compounds from Usnea undulata Stirton.
Sultana N, Afolayan AJ.J Asian Nat Prod Res. 2011 Dec;13(12):1158-64. doi: 10.1080/10286020.2011.622720.
- 18. Intraerythrocytic stages of Plasmodium falciparum biosynthesize vitamin E.
Sussmann RA, Angeli CB, Peres VJ, Kimura EA, Katzin AM.FEBS Lett. 2011 Dec 15;585(24):3985-91. doi: 10.1016/j.febslet.2011.11.005. Epub 2011 Nov 12.
- 19. Evaluation of portable Raman spectrometer with 1064 nm excitation for geological and forensic applications.
Vítek P, Ali EM, Edwards HG, Jehli?ka J, Cox R, Page K.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Feb;86:320-7. doi: 10.1016/j.saa.2011.10.043. Epub 2011 Oct 20.
- 20. Effect of usnic acid on Candida orthopsilosis and C. parapsilosis.
Pires RH, Lucarini R, Mendes-Giannini MJ.Antimicrob Agents Chemother. 2012 Jan;56(1):595-7. doi: 10.1128/AAC.05348-11. Epub 2011 Oct 17.