Standard Herbal Extract

Ginseng Extract Safety Tips

Handling of Ginseng Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Cerebroprotective effects of Red ginseng extract pretreatment against ischemia-induced oxidative stress and apoptosis.
  Cheon SY, Cho KJ, Lee JE, Kim HW, Lee SK, Kim HJ, Kim GW.Int J Neurosci. 2012 Dec 17. [Epub ahead of print]
• 2. Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats.
  Han SY, Li HX, Ma X, Zhang K, Ma ZZ, Tu PF.J Ethnopharmacol. 2012 Dec 10. doi:pii: S0378-8741(12)00813-6.  10.1016/j.jep.2012.11.036. [Epub ahead of print]
• 3. [Comparison on appearance and non-ginsenoside composition in Panax ginseng and its products processed from different producing areas in northeast China].
  Wu X, Ye Z, Guo Q, Lu Z.Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2383-7. Chinese.
• 4. Korean red ginseng (Panax ginseng) prevents obesity by inhibiting angiogenesis in high fat diet-induced obese C57BL/6J mice.
  Park D, Lee H, Yoon M.Food Chem Toxicol. 2012 Dec 8. doi:pii: S0278-6915(12)00859-9.  10.1016/j.fct.2012.11.052. [Epub ahead of print]
• 5. Cytotoxicity of herbal extracts used for treatment of prostatic disease             on head and neck carcinoma cell lines and non-malignant primary mucosal cells.
  Schmidt M, Polednik C, Roller J, Hagen R.Oncol Rep. 2013 Feb;29(2):628-36. doi: 10.3892/or.2012.2145. Epub 2012 Nov 19.
• 6. Red ginseng extract attenuates kainate-induced excitotoxicity by antioxidative effects.
  Han JY, Ahn SY, Oh EH, Nam SY, Hong JT, Oh KW, Lee MK.Evid Based Complement Alternat Med. 2012;2012:479016. doi: 10.1155/2012/479016. Epub 2012 Oct 23.
• 7. Increased effects of ginsenosides on the expression of cholesterol 7α-hydroxylase but not the bile salt export pump are involved in cholesterol metabolism.
  Kawase A, Yamada A, Gamou Y, Tahara C, Takeshita F, Murata K, Matsuda H, Samukawa K, Iwaki M.J Nat Med. 2012 Oct 30. [Epub ahead of print]
• 8. Effects of Korean red ginseng extracts on neural tube defects and impairment of social interaction induced by prenatal exposure to valproic acid.
  Kim P, Park JH, Kwon KJ, Kim KC, Kim HJ, Lee JM, Kim HY, Han SH, Shin CY.Food Chem Toxicol. 2012 Oct 24;51C:288-296. doi: 10.1016/j.fct.2012.10.011. [Epub ahead of print]
• 9. Panax ginseng reduces oxidative stress and restores antioxidant capacity in aged rats.
  Ramesh T, Kim SW, Hwang SY, Sohn SH, Yoo SK, Kim SK.Nutr Res. 2012 Sep;32(9):718-26. doi: 10.1016/j.nutres.2012.08.005.
• 10. Panax ginseng: a newly identified cause of gynecomastia.
  Kakisaka Y, Ohara T, Tozawa H, Sato S, Katayama S, Suzuki T, Hino-Fukuyo N, Kure S.Tohoku J Exp Med. 2012;228(2):143-5.
• 11. Korean red ginseng (Panax ginseng) ameliorates type 1 diabetes and restores immune cell compartments.
  Hong YJ, Kim N, Lee K, Hee Sonn C, Eun Lee J, Tae Kim S, Ho Baeg I, Lee KM.J Ethnopharmacol. 2012 Nov 21;144(2):225-33. doi: 10.1016/j.jep.2012.08.009. Epub 2012 Aug 19.
• 12. Safety and Tolerability of Panax ginseng Root Extract: A Randomized, Placebo-Controlled, Clinical Trial in Healthy Korean Volunteers.
  Lee NH, Yoo SR, Kim HG, Cho JH, Son CG.J Altern Complement Med. 2012 Nov;18(11):1061-9. doi: 10.1089/acm.2011.0591. Epub 2012 Aug 21.
• 13. Nardostachys jatamansi Protects Against Cold Restraint Stress Induced Central Monoaminergic and Oxidative Changes in Rats.
  Lyle N, Chakrabarti S, Sur T, Gomes A, Bhattacharyya D.Neurochem Res. 2012 Dec;37(12):2748-57. doi: 10.1007/s11064-012-0867-1. Epub 2012 Aug 19.
• 14. Studies on structures and activities of initial Maillard reaction products by electrospray ionisation mass spectrometry combined with liquid chromatography in processing of red ginseng.
  Du QQ, Liu SY, Xu RF, Li M, Song FR, Liu ZQ.Food Chem. 2012 Nov 15;135(2):832-8. doi: 10.1016/j.foodchem.2012.04.126. Epub 2012 May 8.
• 15. [Study on optimization method of dynamic extraction process].
  Wang D, Zhang J, Zhang L, Wang Y, Liu A.Zhongguo Zhong Yao Za Zhi. 2012 May;37(10):1388-91. Chinese.
• 16. More accurate matrix-matched quantification using standard superposition method for herbal medicines.
  Liu Y, Shi XW, Liu EH, Sheng LS, Qi LW, Li P.J Chromatogr A. 2012 Sep 7;1254:43-50. doi: 10.1016/j.chroma.2012.07.020. Epub 2012 Jul 13.
• 17. Active compounds and distinctive sensory features provided by American ginseng (Panax quinquefolius L.) extract in a new functional milk beverage.
  Tárrega A, Salvador A, Meyer M, Feuillère N, Ibarra A, Roller M, Terroba D, Madera C, Iglesias JR, Echevarría J, Fiszman S.J Dairy Sci. 2012 Aug;95(8):4246-55. doi: 10.3168/jds.2012-5341.
• 18. The hypoglycemic effects of American red ginseng (Panax quinquefolius L.) on a diabetic mouse model.
  Yoo KM, Lee C, Lo YM, Moon B.J Food Sci. 2012 Jul;77(7):H147-52. doi: 10.1111/j.1750-3841.2012.02748.x.
• 19. Effects of an aqueous extract of North American ginseng on MOG(35-55)-induced EAE in mice.
  Bowie LE, Roscoe WA, Lui EM, Smith R, Karlik SJ.Can J Physiol Pharmacol. 2012 Jul;90(7):933-9. doi: 10.1139/y2012-092. Epub 2012 Jun 21.
• 20. Biotransformation of furannoligularenone by transgenic crown galls of Panax quinquefolium.
  Yan C, Wang J, Duan G, Yu R.Pharmacogn Mag. 2012 Apr;8(30):124-8. doi: 10.4103/0973-1296.96555.

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