Deoxyarbutin Safety Tips
Handling of Deoxyarbutin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
References
- 1. DeoxyArbutin and Its Derivatives Inhibit Tyrosinase Activity and Melanin Synthesis Without Inducing Reactive Oxygen Species or Apoptosis.
Chawla S, Kvalnes K, Delong MA, Wickett R, Manga P, Boissy RE.J Drugs Dermatol. 2012 Oct 1;11(10):e28-34. - 2. Study on the Stability of DeoxyArbutin in an Anhydrous Emulsion System.
Lin CC, Yang CH, Chang NF, Wu PS, Chen YS, Lee SM, Chen CW.Int J Mol Sci. 2011;12(9):5946-54. doi: 10.3390/ijms12095946. Epub 2011 Sep 15. - 3. Determination of the Thermodegradation of deoxyArbutin in Aqueous Solution by High Performance Liquid Chromatography.
Yang CH, Chen YS, Lai JS, Hong WW, Lin CC.Int J Mol Sci. 2010 Oct 15;11(10):3977-87. doi: 10.3390/ijms11103977. - 4. Effects of hydroquinone and its glucoside derivatives on melanogenesis and antioxidation: Biosafety as skin whitening agents.
Hu ZM, Zhou Q, Lei TC, Ding SF, Xu SZ.J Dermatol Sci. 2009 Sep;55(3):179-84. doi: 10.1016/j.jdermsci.2009.06.003. Epub 2009 Jul 1. - 5. Mechanism of tyrosinase inhibition by deoxyArbutin and its second-generation derivatives.
Chawla S, deLong MA, Visscher MO, Wickett RR, Manga P, Boissy RE.Br J Dermatol. 2008 Dec;159(6):1267-74. doi: 10.1111/j.1365-2133.2008.08864.x. Epub 2008 Sep 20. - 6. Comparative efficacy and safety of deoxyarbutin, a new tyrosinase-inhibiting agent.
Hamed SH, Sriwiriyanont P, deLong MA, Visscher MO, Wickett RR, Boissy RE.J Cosmet Sci. 2006 Jul-Aug;57(4):291-308. - 7. DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency.
Boissy RE, Visscher M, DeLong MA.Exp Dermatol. 2005 Aug;14(8):601-8. - 8. Effect of deoxyarbutin on melanogenesis: in vivo comparison with other melanogenesis inhibitor.
Hamed SH, Sriwiiyanont P, Wickett RR, Boissy R.J Cosmet Sci. 2004 Jan-Feb;55(1):118-9. No abstract available.
Details
Product Name | Deoxyarbutin |
---|---|
CAS No. | 53936-56-4 |
Molecular Formula | C11H14O3 |
Molecular Weight | 194.23 |
Botanical Source | Synthesized from Arbutin |
Purity | 98% HPLC |
Appearance | Off-white powder |
Package | 25 kg/drum |
Storage | Stored in cool & dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
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