Botanical Ingredient

Gardenoside Safety Tips

Handling of Gardenoside should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. [Simultaneous determination of eight iridoid glycosides in Gardeniae fructus by HPLC].
  Liu W, Fan J, Gao Y, Qiu X, Zhuang H, Zhao Z.Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2417-21. Chinese.
• 2. [Comparision of adsorption-desorption dynamics of huanglian jiedu decoction using different macroporous resins combinations].
  Qiu B, Li H, Pan L, Zhu H, Guo L.Zhongguo Zhong Yao Za Zhi. 2011 Aug;36(15):2056-60. Chinese.
• 3. [Ultrafiltration process of model system of Huanglian Jiedu decoction].
  Dong J, Zhu H, Guo L.Zhongguo Zhong Yao Za Zhi. 2009 Oct;34(19):2458-62. Chinese.
• 4. Iridoid glycosides from Gardeniae Fructus for treatment of ankle sprain.
  Chen QC, Zhang WY, Youn U, Kim H, Lee I, Jung HJ, Na M, Min BS, Bae K.Phytochemistry. 2009 Apr;70(6):779-84. doi: 10.1016/j.phytochem.2009.03.008.
• 5. Isolation and purification of iridoid glycosides from Gardenia jasminoides Ellis by isocratic reversed-phase two-dimensional preparative high-performance liquid chromatography with column switch technology.
  Zhou T, Zhao W, Fan G, Chai Y, Wu Y.J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):296-301. Epub 2007 Aug 30.
• 6. Iridoid glucosides from the fruit of Genipa americana.
  Ono M, Ueno M, Masuoka C, Ikeda T, Nohara T.Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1342-4.
• 7. [Studies on purification of the extract of fructus Gardeniae for injection by macroreticular resins].
  Chen G, Hou SX, Ye LM, Hu P.Zhongguo Zhong Yao Za Zhi. 2005 Feb;30(3):188-90. Chinese.
• 8. [Simultaneous determination of 3 kinds of components in Gardenia by high-performance liquid chromatography under different UV-vis wave length].
  Xu Y, Cao J, Wang YM, Luo GA.Yao Xue Xue Bao. 2003 Jul;38(7):543-6. Chinese.
• 9. Iridoid glucosides from Randia spinosa (Rubiaceae).
  Hamerski L, Furlan M, Silva DH, Cavalheiro AJ, Eberlin MN, Tomazela DM, da Silva Bolzani V.Phytochemistry. 2003 Jun;63(4):397-400.
• 10. [Content analysis on gardenoside in grown and ungrown fruits of Gardenia from different habitats].
  Fu X, Chu X, Fan J, Lu W.Zhong Yao Cai. 2000 Dec;23(12):754-6. Chinese.
• 11. Effects of different compounding of formulae on content of gardenoside in Yin Chen Hao decoction.
  Liang G, Cao P, Chai L, Xian F, Li X.J Tradit Chin Med. 2002 Mar;22(1):55-60.
• 12. Liver-protective activities of aucubin derived from traditional oriental medicine.
  Chang IM.Res Commun Mol Pathol Pharmacol. 1998 Nov;102(2):189-204.
• 13. [Correlativity among biological characteristics of Gardenia jasminoides Eills].
  Zhou C, Zhang X, Luo J, Yu H.Zhongguo Zhong Yao Za Zhi. 1997 Apr;22(4):208-10, 253. Chinese.
• 14. [Comparison of 4 extraction methods for antidotal granules of Coptis].
  Sun X, Zhang Z, Lu L, Li Y.Zhongguo Zhong Yao Za Zhi. 1996 Aug;21(8):474-6, 510. Chinese.
• 15. Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein kinases.
  Yamazaki M, Chiba K, Mohri T.Biol Pharm Bull. 1996 Jun;19(6):791-5.
• 16. Hypoglycemic activity and structure-activity relationship of iridoidal glycosides.
  Miura T, Nishiyama Y, Ichimaru M, Moriyasu M, Kato A.Biol Pharm Bull. 1996 Jan;19(1):160-1.
• 17. [A comparative study on the chemical constituents of cultivated and wild fructus Gardeniae].
  Gao Z, Jiang P, Wu Q, Wang J.Zhongguo Zhong Yao Za Zhi. 1995 Nov;20(11):654-6, 702. Chinese.
• 18. [HPLC determination of iridoids in Cape jasmine Frvit (Zhizi)].
  Liu Y, Lu GR, Lu J.Zhongguo Zhong Yao Za Zhi. 1993 May;18(5):298-9, 319. Chinese.
• 19. Formation of nitrogen-containing metabolites from geniposide and gardenoside by human intestinal bacteria.
  Kawata Y, Hattori M, Akao T, Kobashi K, Namba T.Planta Med. 1991 Dec;57(6):536-42.
• 20. Production of anti-tumor-promoting iridoid glucosides in Genipa americana and its cell cultures.
  Ueda S, Iwahashi Y, Tokuda H.J Nat Prod. 1991 Nov-Dec;54(6):1677-80.

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