Botanical Ingredient

Isoimperatorin Safety Tips

Handling of Isoimperatorin should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. [A new natural product from root of Angelica dahurica cv. Qibaizhi].
  Zhao A, Yang X, Yang X, Liu J, Wang Q, Wang W.Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2400-7. Chinese.
• 2. Determination of Cnidilin and Its Two Metabolites in Rat Plasma by High-performance Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry.
  Zhu H, Liu P, Shi X, Xu H, Ren Y, Wang Q, Zhang L.Planta Med. 2012 Nov 27. [Epub ahead of print]
• 3. Coumarins from Angelica archangelica Linn. and their effects on anxiety-like behavior.
  Kumar D, Bhat ZA, Kumar V, Shah MY.Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:180-6. doi: 10.1016/j.pnpbp.2012.08.004. Epub 2012 Aug 29.
• 4. [Fingerprint analysis of Glehniae Radix by TLC].
  Su X, Li XK, Wu T, Zhang T, Wang ZT.Zhong Yao Cai. 2012 Feb;35(2):210-3. Chinese.
• 5. [Chemical constituents contained in seeds of Notopterygium franchetii].
  Zhang Y, Jiang S, Xu K, Shi H, Zhou Y, Deng W, Ding L, Peng S.Zhongguo Zhong Yao Za Zhi. 2012 Apr;37(7):941-5. Chinese.
• 6. Comparison of two species of Notopterygium by high-performance liquid chromatography-photodiode array detection-electrospray ionization tandem mass spectrometry.
  Liu GQ, Dong J, Wang H, Hashi Y, Chen SZ.Eur J Mass Spectrom (Chichester, Eng). 2012;18(1):59-69.
• 7. [Fingerprint of Angelica polymorpha by HPLC].
  Lu J, Wang Q, Xu J, He D, Ruan X, Hu X.Zhongguo Zhong Yao Za Zhi. 2012 Mar;37(6):832-5. Chinese.
• 8. Simultaneous analysis of six major compounds in Osterici Radix and Notopterygii Rhizoma et Radix by HPLC and discrimination of their origins from chemical fingerprint analysis.
  Kim S, Kim KY, Han CS, Ki KS, Min KJ, Zhang X, Whang WK.Arch Pharm Res. 2012 Mar;35(4):691-9. doi: 10.1007/s12272-012-0413-3. Epub 2012 May 3.
• 9. Geographical variation of the furanocoumarin composition of the fruits of Icelandic Angelica archangelica.
  Sigurdsson S, Jonsdottir S, Gudbjarnason S.Z Naturforsch C. 2012 Jan-Feb;67(1-2):1-7.
• 10. Pressurized liquid extraction of coumarins from fruits of Heracleum leskowii with application of solvents with different polarity under increasing temperature.
  Skalicka-Wo?niak K, G?owniak K.Molecules. 2012 Apr 5;17(4):4133-41. doi: 10.3390/molecules17044133.
• 11. Larvicidal activity of Cnidium monnieri fruit coumarins and structurally related compounds against insecticide-susceptible and insecticide-resistant Culex pipiens pallens and Aedes aegypti.
  Wang Z, Kim JR, Wang M, Shu S, Ahn YJ.Pest Manag Sci. 2012 Jul;68(7):1041-7. doi: 10.1002/ps.3265. Epub 2012 Mar 5.
• 12. Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice.
  Wang X, Lou YJ, Wang MX, Shi YW, Xu HX, Kong LD.Toxicol Lett. 2012 Feb 25;209(1):67-77. doi: 10.1016/j.toxlet.2011.11.030. Epub 2011 Dec 7.
• 13. Study on pharmacokinetics and tissue distribution of pteryxin in mice by ultra-pressure liquid chromatography with tandem mass spectrometry.
  Wang J, Ma Y, Li W, Hu F, Chen T, Shen X, Feng S.Biomed Chromatogr. 2012 Jul;26(7):802-7. doi: 10.1002/bmc.1733. Epub 2011 Nov 20.
• 14. [Determination of supermolecular inclusion constants of hydroxylpropyl-beta-cylcodextrin with imperatorin and isoimperatorin by phase solubility method].
  Li C, Wang CH, Zeng AG, Yang X, Yang GD.Zhong Yao Cai. 2011 Jun;34(6):965-7. Chinese.
• 15. [Determination of imperatorin and isoimperatorin in cosmetics by high performance liquid chromatography-tandem mass spectrometry].
  Chen J, Xu J, Xiong L.Se Pu. 2011 May;29(5):454-7. Chinese.
• 16. Antigenotoxic activity of naturally occurring furanocoumarins.
  Marumoto S, Oda Y, Miyazawa M.Environ Mol Mutagen. 2011 Oct;52(8):646-57. doi: 10.1002/em.20665. Epub 2011 Jul 22.
• 17. Simultaneous quantification of 17 constituents from Yuanhu Zhitong tablet using rapid resolution liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry.
  Zhang Y, Xu H, Chen X, Chen C, Wang H, Meng F, Yang H, Huang L.J Pharm Biomed Anal. 2011 Nov 1;56(3):497-504. doi: 10.1016/j.jpba.2011.06.008. Epub 2011 Jun 16.
• 18. Identification and quantification of coumarins in Peucedanum ostruthium (L.) Koch by HPLC-DAD and HPLC-DAD-MS.
  Vogl S, Zehl M, Picker P, Urban E, Wawrosch C, Reznicek G, Saukel J, Kopp B.J Agric Food Chem. 2011 May 11;59(9):4371-7. doi: 10.1021/jf104772x. Epub 2011 Mar 22.
• 19. [Dynamic research of growth, N, P, K and active ingredients in Angelica dahurica var. formosana from Sichuan province].
  Chen J, Wu W, Hou K, Zai J.Zhongguo Zhong Yao Za Zhi. 2010 Nov;35(21):2812-7. Chinese.
• 20. [Quantitative analysis of five components in the rhizome of Angelica polymorpha by RP-HPLC under different UV wavelengths].
  Liang F, Yang Y, Zhao Y, Yu N, Wang J.Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(19):2581-4. Chinese.

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