Botanical Ingredient

Isorhamnetin Safety Tips

Handling of Isorhamnetin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. [Flavonoid glycosides from dried and nearly ripe fruits of Evodia rutaecarpa].
  Hu CQ, Yang XB, Yang XW, Liu JX.Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2571-5. Chinese.
• 2. Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside.
  Ku SK, Kim TH, Lee S, Kim SM, Bae JS.Food Chem Toxicol. 2012 Dec 5. doi:pii: S0278-6915(12)00847-2.  10.1016/j.fct.2012.11.040. [Epub ahead of print]
• 3. [Effects of isorhamnetin on CYP3A4 and herb-drug interaction].
  Ding LL, Zhang JJ, Dou W.Yao Xue Xue Bao. 2012 Aug;47(8):1006-10. Chinese.
• 4. Dose-response to 3 months of quercetin-containing supplements on metabolite and quercetin conjugate profile in adults.
  Cialdella-Kam L, Nieman DC, Sha W, Meaney MP, Knab AM, Shanely RA.Br J Nutr. 2012 Nov 14:1-11. [Epub ahead of print]
• 5. Two new compounds from Potentilla multicaulis Bunge.
  Jia L, Wang J, Lv C, Xu T, He L, Dong Y, Lu J.Nat Prod Res. 2012 Nov 13. [Epub ahead of print]
• 6. Quantification of flavonoids in black rice by liquid chromatography-negative electrospray ionization tandem mass spectrometry.
  Sriseadka T, Wongpornchai S, Rayanakorn M.J Agric Food Chem. 2012 Nov 28;60(47):11723-32. doi: 10.1021/jf303204s. Epub 2012 Nov 16.
• 7. Flavonoids products from Nitraria retusa leaves promote lymphoblastoid cells apoptosis.
  Jihed B, Bhouri W, Ben Sghaier M, Bouhlel I, Kriffi M, Skandrani I, Dijoux FM, Ghedira K, Chekir-Ghedira L.Nutr Cancer. 2012;64(7):1095-102. doi: 10.1080/01635581.2012.717680.
• 8. Metabolome Classification of Brassica napus L. Organs via UPLC-QTOF-PDA-MS and Their Anti-oxidant Potential.
  Farag MA, Sharaf Eldin MG, Kassem H, Abou El Fetouh M.Phytochem Anal. 2012 Oct 11. doi: 10.1002/pca.2408. [Epub ahead of print]
• 9. An optimized method for analysis of phenolic compounds in buds, leaves, and fruits of black currant ( Ribes nigrum L.).
  Vagiri M, Ekholm A, Andersson SC, Johansson E, Rumpunen K.J Agric Food Chem. 2012 Oct 24;60(42):10501-10. doi: 10.1021/jf303398z. Epub 2012 Oct 15.
• 10. Chemical composition and biological activities of polar extracts and essential oil of rose-scented geranium, Pelargonium graveolens.
  Boukhris M, Simmonds MS, Sayadi S, Bouaziz M.Phytother Res. 2012 Oct 2. doi: 10.1002/ptr.4853. [Epub ahead of print]
• 11. Novel insight into qualitative standardization of Polygoni avicularis herba (Ph. Eur.).
  Granica S, Piwowarski JP, Pop?awska M, Jakubowska M, Borzym J, Kiss AK.J Pharm Biomed Anal. 2013 Jan;72:216-22. doi: 10.1016/j.jpba.2012.08.027. Epub 2012 Sep 10.
• 12. [Study on phenolic constituents of Amomum villosum].
  Chen C, Fu C, Ye WC, Zhou GX.Zhong Yao Cai. 2012 Apr;35(4):571-3. Chinese.
• 13. Studies on the antioxidant potential of flavones of Allium vineale isolated from its water-soluble fraction.
  Demirtas I, Erenler R, Elmastas M, Goktasoglu A.Food Chem. 2013 Jan 1;136(1):34-40. doi: 10.1016/j.foodchem.2012.07.086. Epub 2012 Jul 27.
• 14. Evaluation of the inhibitory effects of quercetin-related flavonoids and tea catechins on the monoamine oxidase-A reaction in mouse brain mitochondria.
  Bandaruk Y, Mukai R, Kawamura T, Nemoto H, Terao J.J Agric Food Chem. 2012 Oct 17;60(41):10270-7. doi: 10.1021/jf303055b. Epub 2012 Oct 8.
• 15. [Chemical constituents of Neoalsomitra integrifoliola].
  Su D, Tang W, Yu S, Liu Y, Qu J, Yu D.Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(11):1593-6. Chinese.
• 16. Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer.
  Ramachandran L, Manu KA, Shanmugam MK, Li F, Siveen KS, Vali S, Kapoor S, Abbasi T, Surana R, Smoot DT, Ashktorab H, Tan P, Ahn KS, Yap CW, Kumar AP, Sethi G.J Biol Chem. 2012 Nov 2;287(45):38028-40. doi: 10.1074/jbc.M112.388702. Epub 2012 Sep 19.
• 17. Inhibitory effect of Ginkgo biloba extract on fatty liver: regulation of carnitine palmitoyltransferase 1a and fatty acid metabolism.
  Wang SD, Xie ZQ, Chen J, Wang K, Wei T, Zhao AH, Zhang QH.J Dig Dis. 2012 Oct;13(10):525-35. doi: 10.1111/j.1751-2980.2012.00627.x.
• 18. Screening and quantitative analysis of antioxidants in the fruits of Livistona chinensis R. Br using HPLC-DAD-ESI/MS coupled with pre-column DPPH assay.
  Yao H, Chen Y, Shi P, Hu J, Li S, Huang L, Lin J, Lin X.Food Chem. 2012 Dec 15;135(4):2802-7. doi: 10.1016/j.foodchem.2012.07.076. Epub 2012 Jul 25.
• 19. HPLC-MSn identification and quantification of flavonol glycosides in 28 wild and cultivated berry species.
  Mikulic-Petkovsek M, Slatnar A, Stampar F, Veberic R.Food Chem. 2012 Dec 15;135(4):2138-46. doi: 10.1016/j.foodchem.2012.06.115. Epub 2012 Jul 14.
• 20. Antiadipogenic activity of isohamnetin 3-O-β-D-glucopyranoside from Salicornia herbacea.
  Kong CS, Seo Y.Immunopharmacol Immunotoxicol. 2012 Dec;34(6):907-11. doi: 10.3109/08923973.2012.670643. Epub 2012 Sep 17.

Details