Standard Herbal Extract

Burdock Root Extract Safety Tips

Handling of Burdock Root Extract should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

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• 6. Liver targeting effect of vinegar-baked Radix Bupleuri on rhein in rats.
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• 7. Macrophage immunomodulatory activity of the polysaccharides from the roots of Bupleurum smithii var. parvifolium.
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• 8. Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS.
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• 9. Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins.
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• 10. Preparation of nasal temperature-sensitive in situ gel of Radix Bupleuri and evaluation of the febrile response mechanism.
  Chen E, Chen J, Cao SL, Zhang QZ, Jiang XG.Drug Dev Ind Pharm. 2010 Apr;36(4):490-6. doi: 10.3109/03639040903264371.
• 11. Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis.
  Tian RT, Xie PS, Liu HP.J Chromatogr A. 2009 Mar 13;1216(11):2150-5. doi: 10.1016/j.chroma.2008.10.127. Epub 2008 Nov 28.
• 12. A novel nasal delivery system of a Chinese traditional medicine, Radix Bupleuri, based on the concept of ion-activated in situ gel.
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• 13. A novel method of protein extraction from perennial Bupleurum root for 2-DE.
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• 14. Pharmacology and toxicology of Bupleurum root-containing Kampo medicines in clinical use.
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• 15. A novel analytical ELISA-based methodology for pharmacologically active saikosaponins.
  Zhu S, Shimokawa S, Shoyama Y, Tanaka H.Fitoterapia. 2006 Feb;77(2):100-8. Epub 2006 Jan 10.
• 16. [Effect of radix bupleuri extract on cardiomyocyte apoptosis related genes expression in mouse infected with coxsackie virus B3m].
  Wang XF, Zhou L, Nan CH.Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Oct;25(10):925-8. Chinese.
• 17. Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in vitro and in vivo.
  Cheng YL, Lee SC, Lin SZ, Chang WL, Chen YL, Tsai NM, Liu YC, Tzao C, Yu DS, Harn HJ.Cancer Lett. 2005 May 26;222(2):183-93. Epub 2004 Nov 19.
• 18. Vasorelaxant effects of the chloroformic crude extract of Bupleurum fruticosum L. (Umbelliferae) roots on rat thoracic aorta.
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• 19. The antiproliferative activity of saponin-enriched fraction from Bupleurum Kaoi is through Fas-dependent apoptotic pathway in human non-small cell lung cancer A549 cells.
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• 20. Dual inhibition of cyclooxygenase-1 and 5-lipoxygenase by aerial part of Bupleurum fruticescens methanol extract.
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