Standard Herbal Extract

Phaseolus Calcaratus Bean Extract Safety Tips

Handling of Phaseolus Calcaratus Bean Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Self-nanoemulsifying drug delivery system of persimmon leaf extract: Optimization and bioavailability studies.
  Li W, Yi S, Wang Z, Chen S, Xin S, Xie J, Zhao C.Int J Pharm. 2011 Nov 25;420(1):161-71. doi: 10.1016/j.ijpharm.2011.08.024. Epub 2011 Aug 22.
• 2. Evaluation of the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves.
  Sun L, Zhang J, Lu X, Zhang L, Zhang Y.Food Chem Toxicol. 2011 Oct;49(10):2689-96. doi: 10.1016/j.fct.2011.07.042. Epub 2011 Jul 23.
• 3. Persimmon leaf extract inhibits the ATM activity during DNA damage response induced by Doxorubicin in A549 lung adenocarcinoma cells.
  Kawakami K, Nishida H, Tatewaki N, Nakajima Y, Konishi T, Hirayama M.Biosci Biotechnol Biochem. 2011;75(4):650-5. Epub 2011 Apr 22.
• 4. Investigation of plant extracts in traditional medicine of the Brazilian Cerrado against protozoans and yeasts.
  Albernaz LC, de Paula JE, Romero GA, Silva Mdo R, Grellier P, Mambu L, Espindola LS.J Ethnopharmacol. 2010 Aug 19;131(1):116-21. doi: 10.1016/j.jep.2010.06.011. Epub 2010 Jun 22.
• 5. Chemistry of secondary polyphenols produced during processing of tea and selected foods.
  Tanaka T, Matsuo Y, Kouno I.Int J Mol Sci. 2009 Dec 28;11(1):14-40. doi: 10.3390/ijms11010014.
• 6. 24-hydroxyursolic acid from the leaves of the Diospyros kaki (Persimmon) induces apoptosis by activation of AMP-activated protein kinase.
  Khanal P, Oh WK, Thuong PT, Cho SD, Choi HS.Planta Med. 2010 May;76(7):689-93. doi: 10.1055/s-0029-1240678. Epub 2009 Dec 3.
• 7. Effects and action mechanism of Diospyros kaki on the differentiation of human leukemia HL-60 cells.
  Kim SH, Cho SS, Simkhada JR, Park SJ, Lee HJ, Kim TS, Yoo JC.Oncol Rep. 2010 Jan;23(1):89-95.
• 8. Biological synthesis of platinum nanoparticles using Diopyros kaki leaf extract.
  Song JY, Kwon EY, Kim BS.Bioprocess Biosyst Eng. 2010 Jan;33(1):159-64. doi: 10.1007/s00449-009-0373-2. Epub 2009 Aug 23.
• 9. Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.
  Thuong PT, Lee CH, Dao TT, Nguyen PH, Kim WG, Lee SJ, Oh WK.J Nat Prod. 2008 Oct;71(10):1775-8. doi: 10.1021/np800298w. Epub 2008 Sep 18.
• 10. Cytotoxic properties of Diospyros seychellarum extract.
  Buenz EJ, Bauer BA, Motley TJ, Limburg PJ.J Toxicol Sci. 2007 Dec;32(5):487-93.
• 11. Neuroprotective effects of a standardized extract of Diospyros kaki leaves on MCAO transient focal cerebral ischemic rats and cultured neurons injured by glutamate or hypoxia.
  Bei W, Peng W, Zang L, Xie Z, Hu D, Xu A.Planta Med. 2007 Jun;73(7):636-43. Epub 2007 Jun 22.
• 12. A new aurone and two rare metabolites from the leaves of Diospyros melanoxylon.
  Mallavadhani UV, Mahapatra A.Nat Prod Res. 2005 Jan;19(1):91-7.
• 13. Antibacterial activity of plants used in cooking for aroma and taste.
  Hara-Kudo Y, Kobayashi lA, Sugita-Konishi Y, Kondo K.J Food Prot. 2004 Dec;67(12):2820-4.
• 14. Structural analysis of a pectic polysaccharide from the leaves of Diospyros kaki.
  Duan J, Zheng Y, Dong Q, Fang J.Phytochemistry. 2004 Mar;65(5):609-15.
• 15. Pheophorbide A-methyl ester, Acyl-CoA: cholesterol acyltransferase inhibitor from Diospyros kaki.
  Rho MC, Chung MY, Song HY, Kwon OE, Lee SW, Baek JA, Jeune KH, Kim K, Lee HS, Kim YK.Arch Pharm Res. 2003 Sep;26(9):716-8.
• 16. Oral administration of persimmon leaf extract ameliorates skin symptoms and transepidermal water loss in atopic dermatitis model mice, NC/Nga.
  Matsumoto M, Kotani M, Fujita A, Higa S, Kishimoto T, Suemura M, Tanaka T.Br J Dermatol. 2002 Feb;146(2):221-7.
• 17. Persimmon leaf extract and astragalin inhibit development of dermatitis and IgE elevation in NC/Nga mice.
  Kotani M, Matsumoto M, Fujita A, Higa S, Wang W, Suemura M, Kishimoto T, Tanaka T.J Allergy Clin Immunol. 2000 Jul;106(1 Pt 1):159-66.
• 18. Antimicrobial potentials of Diospyros mespiliformis (Ebenaceae).
  Adeniyi BA, Odelola HA, Oso BA.Afr J Med Med Sci. 1996 Sep;25(3):221-4.
• 19. Antifertility effects of leaf extracts of some plants in male rats.
  Choudhary DN, Singh JN, Verma SK, Singh BP.Indian J Exp Biol. 1990 Aug;28(8):714-6.
• 20. Preliminary investigation of in-vitro antimicrobial activity of two Nigerian Diospyros species (Ebenaceae).
  Odelola HA, Okorosobo VI.Afr J Med Med Sci. 1988 Sep;17(3):167-70.

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