Indirubin
Indirubin, a natural active component of Indigo naturalis, is a red isomer of indigo. With the CAS number 479-41-4 and a purity of ≥98% as determined by HPLC, Indirubin has been historically recognized for its efficacy in traditional Chinese medicine, particularly in treating chronic myelogenous leukemia (CML) and other types of cancer. Recent studies have explored its potential as an inhibitor of cyclin-dependent kinases (CDKs), showcasing its broader therapeutic applications in oncology and neurodegenerative diseases.
Product Details:
- Product Name: Indirubin
- CAS Number: 479-41-4
- Purity: ≥98% HPLC
- Molecular Formula: C16H10N2O2
- Molecular Weight: 262.26 g/mol
- Appearance: Red to purple crystalline powder
- Solubility: Soluble in DMSO, methanol, and slightly soluble in water
- Storage: Store at -20°C, protected from light and moisture
Features & Benefits:
- Anticancer Activity: Demonstrated efficacy in inhibiting the proliferation of cancer cells, especially in leukemia treatment.
- CDK Inhibition: Acts as a potent inhibitor of cyclin-dependent kinases, offering potential therapeutic benefits in cancer therapy and neurodegenerative disease management.
- Traditional and Modern Use: Bridges the gap between traditional medicine and contemporary pharmacological research.
- Neuroprotective Potential: Explored for its role in neuroprotection, suggesting applications in treating neurodegenerative conditions.
Applications:
- Pharmaceutical Research: Investigated for its anticancer properties and potential applications in treating various cancers and neurodegenerative diseases.
- Nutraceuticals: Utilized in dietary supplements for its health-promoting effects, based on traditional medicine practices.
- Biomedical Studies: A subject of ongoing research to understand its mechanisms of action, efficacy, and safety profile in various therapeutic contexts.
- Herbal Medicine: Incorporated into traditional herbal formulations for its therapeutic benefits.
Safety & Compliance:
- Manufactured under stringent quality control standards to ensure high purity and safety.
- Accompanied by a comprehensive Certificate of Analysis (CoA) for quality assurance.
- Recommended for use by healthcare professionals and researchers familiar with the handling and safety protocols of bioactive compounds.
Packaging:
- Available in 20mg and 1g quantities to support a range of research and development projects.
- Packaged in air-tight containers to maintain stability and ensure product integrity during storage and handling.
Details
| CAS# | 479-41-4 |
|---|---|
| Purity | ≥98%HPLC |
| Package | 20mg;1g |
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