Deoxycholic acid
Deoxycholic acid, a secondary bile acid involved in fat digestion, is utilized medically for its fat-emulsifying properties to treat submental fat, offering a non-surgical option for facial contouring by destroying fat cells.
Deoxycholic acid Overview
Deoxycholic acid’s role in the metabolism of fats and its therapeutic use in cosmetic procedures underscore its versatility and importance in both physiology and medicine.
Deoxycholic acid Key Features
– Natural Source: Produced in the liver from cholic acid and found in bile.
– Function: Facilitates the digestion and absorption of dietary fats and fat-soluble vitamins.
– Medical Use: Approved for cosmetic use in the treatment of moderate to severe submental fat.
Deoxycholic acid Applications
– Digestive Health: Plays a vital role in the normal digestion process as part of bile.
– Cosmetic Treatments: Used in aesthetic medicine to reduce excess fat under the chin, improving facial contouring without surgery.
Deoxycholic acid Mechanism of Action
– Fat Emulsification: Aids in the breakdown and absorption of dietary fats in the intestine.
– Adipocyte Destruction: When used in cosmetic treatments, it destroys fat cells by disrupting their membrane, leading to a reduction in fat deposits.
Functions of Deoxycholic Acid
- Digestive Aid: It emulsifies dietary fats, making them more accessible for digestion by lipases, thereby facilitating the efficient absorption of fats and fat-soluble vitamins (A, D, E, and K) in the small intestine.
- Regulation of Cholesterol Levels: Involved in the elimination of cholesterol from the body by converting cholesterol into bile acids, which can then be excreted.
- Cosmetic Fat Reduction: Specifically targets and destroys adipocytes (fat cells) in targeted areas, such as under the chin, leading to a noticeable reduction in fat and improvement in contour without the need for invasive surgery.
- Promotion of Intestinal Health: By aiding in fat digestion and absorption, it contributes to the overall health of the gastrointestinal tract, preventing fat malabsorption disorders.
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