Aristolochic acid A
Aristolochic Acid A, a compound from Aristolochia plants, known for its nephrotoxic and carcinogenic properties, is crucial for research into its toxicological effects, mechanisms of carcinogenesis, and impact on public health, aiding in the development of safety standards and protective measures.
Product Overview:
Aristolochic Acid A is a natural compound found in the Aristolochia species of plants. While historically used in traditional medicine, significant concerns have arisen about its safety due to its nephrotoxic and carcinogenic properties. Our Aristolochic Acid A is offered for research purposes to provide scientists and medical researchers with the means to study its effects, mechanisms of action, and potential risk factors associated with its use.
Aristolochic acid A Key Features:
– High Purity for Research Use: Ideal for toxicological studies, pharmacokinetics, and understanding the biochemical pathways affected by aristolochic acid.
– Nephrotoxic and Carcinogenic Properties: Facilitates research into the mechanisms of aristolochic acid-induced nephropathy and its links to urothelial cancer.
– DNA Adduct Formation: Enables studies on how aristolochic acid forms DNA adducts, leading to mutations and carcinogenesis.
– Source of Scientific Insight: Provides a basis for developing detection methods for aristolochic acid contamination in herbal products and understanding its environmental impact.
Aristolochic acid A Applications:
– Toxicological Research: Essential for exploring the toxic effects of aristolochic acid on the kidneys and other organs.
– Cancer Research: Offers insights into the carcinogenic mechanisms and potential therapeutic targets for cancers associated with aristolochic acid exposure.
– Pharmacological Studies: Helps in examining the metabolism of aristolochic acid and identifying potential antidotes or protective agents against its harmful effects.
– Regulatory Science: Aids in the development of standards and tests for the detection of aristolochic acid in herbal medicines and supplements.
Aristolochic acid A Functions:
– Investigating Toxic Pathways: Provides a clear understanding of the biochemical and molecular mechanisms leading to aristolochic acid toxicity and carcinogenesis.
– Enhancing Safety Protocols: Contributes to the development of guidelines and safety measures to protect public health from the dangers of aristolochic acid.
– Supporting Public Health Research: Enables comprehensive studies on the epidemiological impact of aristolochic acid and strategies for minimizing exposure risks.
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