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Irinotecan Hydrochloride

Irinotecan Hydrochloride is the hydrochloride salt form of Irinotecan, a widely used chemotherapeutic agent in the treatment of metastatic colorectal cancer. With the CAS number 100286-90-6 and a purity of ≥98% HPLC, Irinotecan Hydrochloride inhibits the enzyme topoisomerase I, which is necessary for DNA replication, leading to the death of rapidly dividing cancer cells. This drug is key in oncology for its efficacy in slowing tumor growth and is approved for use in various cancer treatment protocols.

Product Details:

  • Product Name: Irinotecan Hydrochloride
  • CAS Number: 100286-90-6
  • Purity: ≥98% HPLC
  • Molecular Formula: C33H38N4O6·HCl
  • Molecular Weight: 623.14 g/mol
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in water, DMSO, and ethanol
  • Storage: Store at -20°C, protected from light and moisture

Features & Benefits:

  • Effective Cancer Treatment: Used primarily for the treatment of metastatic colorectal cancer, showing significant improvement in patient outcomes.
  • Mechanism of Action: By inhibiting topoisomerase I, it prevents DNA replication in cancer cells, leading to cell death.
  • Approved Therapeutic: Clinically approved for use, demonstrating a favorable impact in oncology treatments.
  • Research Focus: Continues to be a subject of research for expanding its use to other types of cancer and improving treatment regimens.

Applications:

  • Chemotherapy Regimens: Integral part of combination therapy for metastatic colorectal cancer and investigated for other cancer types.
  • Pharmaceutical Research: Ongoing studies to enhance its efficacy, reduce side effects, and explore new therapeutic applications.
  • Clinical Trials: Active ingredient in numerous clinical trials aiming to find more effective cancer treatments.

Safety & Compliance:

  • Handled with care, adhering to safety guidelines due to its potency and potential side effects.
  • Produced under strict quality control standards to ensure high purity and safety.
  • Accompanied by a comprehensive Certificate of Analysis (CoA) for quality assurance.
  • Recommended for handling and use by healthcare professionals in clinical settings.

Packaging:

  • Available in 20mg and 1g quantities to support a wide range of clinical research and therapeutic applications.
  • Packaged in air-tight containers to ensure stability and maintain integrity during storage.

Details

CAS#

100286-90-6

Purity

≥98%HPLC

Package

20mg;1g










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