Standard Herbal Extract

Andrographis Paniculata Extract Safety Tips

Handling of Andrographis Paniculata Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Adulticidal, repellent, and ovicidal properties of indigenous plant extracts against the malarial vector, Anopheles stephensi (Diptera: Culicidae).
  Panneerselvam C, Murugan K.Parasitol Res. 2012 Nov 29. [Epub ahead of print]
• 2. Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity.
  Guan S, Tee W, Ng D, Chan T, Peh H, Ho W, Cheng C, Mak J, Wong W.Br J Pharmacol. 2012 Nov 12. doi: 10.1111/bph.12054. [Epub ahead of print]
• 3. Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis.
  Sandborn WJ, Targan SR, Byers VS, Rutty DA, Mu H, Zhang X, Tang T.Am J Gastroenterol. 2012 Oct 9. doi: 10.1038/ajg.2012.340. [Epub ahead of print]
• 4. Antioxidative and cytoprotective effects of andrographolide against CCl4-induced hepatotoxicity in HepG2 cells.
  Krithika R, Verma R, Shrivastav P.Hum Exp Toxicol. 2012 Sep 27. [Epub ahead of print]
• 5. Hepatocurative activity of biosynthesized silver nanoparticles fabricated using Andrographis paniculata.
  Suriyakalaa U, Antony JJ, Suganya S, Siva D, Sukirtha R, Kamalakkannan S, Pichiah PB, Achiraman S.Colloids Surf B Biointerfaces. 2013 Feb 1;102:189-94. doi: 10.1016/j.colsurfb.2012.06.039. Epub 2012 Aug 14.
• 6. Formulation and evaluation of herbal anti-acne moisturizer.
  Rasheed A, Shama SN, Joy JM, Reddy BS, Roja C.Pak J Pharm Sci. 2012 Oct;25(4):867-70.
• 7. Quinone reductase (QR) inducers from Andrographis paniculata and identification of molecular target of andrographolide.
  Yuan Y, Ji L, Luo L, Lu J, Ma X, Ma Z, Chen Z.Fitoterapia. 2012 Dec;83(8):1506-13. doi: 10.1016/j.fitote.2012.08.018. Epub 2012 Sep 1.
• 8. Glucose metabolism and diabetogenic gene expression analysis of chloroform fraction of Andrographis paniculata (Nees) whole herb in diabetic albino mice.
  Chaurasia A, Kharya MD, Sharma B, Roy P.J Complement Integr Med. 2012 Aug 10;9(1):Article 21. doi: 10.1515/1553-3840.1632.
• 9. Modulation of cell surface hydrophobicity and attachment of bacteria to abiotic surfaces and shrimp by Malaysian herb extracts.
  Hui YW, Dykes GA.J Food Prot. 2012 Aug;75(8):1507-11. doi: 10.4315/0362-028X.JFP-12-062.
• 10. Immunostimulant, cerebroprotective & nootropic activities of Andrographis paniculata leaves extract in normal & type 2 diabetic rats.
  Radhika P, Annapurna A, Rao SN.Indian J Med Res. 2012 May;135(5):636-41.
• 11. Antidiabetic and antihiperlipidemic effect of Andrographis paniculata (Burm. f.) Nees and andrographolide in high-fructose-fat-fed rats.
  Nugroho AE, Andrie M, Warditiani NK, Siswanto E, Pramono S, Lukitaningsih E.Indian J Pharmacol. 2012 May;44(3):377-81. doi: 10.4103/0253-7613.96343.
• 12. Antifungal activity of Andrographis paniculata extracts and active principles against skin pathogenic fungal strains in vitro.
  Sule A, Ahmed QU, Latip J, Samah OA, Omar MN, Umar A, Dogarai BB.Pharm Biol. 2012 Jul;50(7):850-6. doi: 10.3109/13880209.2011.641021. Epub 2012 May 16.
• 13. A new diterpene from the leaves of Andrographis paniculata Nees.
  Radhika P, Prasad YR, Sowjanya K.Nat Prod Commun. 2012 Apr;7(4):485-6.
• 14. Andrographis paniculata extract protect against isoproterenol-induced myocardial injury by mitigating cardiac dysfunction and oxidative injury in rats.
  Ojha S, Bharti S, Golechha M, Sharma AK, Rani N, Kumari S, Arya DS.Acta Pol Pharm. 2012 Mar-Apr;69(2):269-78.
• 15. Protective effect of hydroalcoholic extract of Andrographis paniculata on ischaemia-reperfusion induced myocardial injury in rats.
  Ojha SK, Bharti S, Joshi S, Kumari S, Arya DS.Indian J Med Res. 2012 Mar;135:414-21.
• 16. Cardiovascular activity of labdane diterpenes from Andrographis paniculata in isolated rat hearts.
  Awang K, Abdullah NH, Hadi AH, Fong YS.J Biomed Biotechnol. 2012;2012:876458. doi: 10.1155/2012/876458. Epub 2012 Mar 28.
• 17. Identification and evaluation of agents isolated from traditionally used herbs against Ophiophagus hannah venom.
  Salama R, Sattayasai J, Gande AK, Sattayasai N, Davis M, Lattmann E.Drug Discov Ther. 2012 Feb;6(1):18-23.
• 18. Anti-cobra venom activity of plant Andrographis paniculata and its comparison with polyvalent anti-snake venom.
  Premendran SJ, Salwe KJ, Pathak S, Brahmane R, Manimekalai K.J Nat Sci Biol Med. 2011 Jul;2(2):198-204. doi: 10.4103/0976-9668.92326.
• 19. Screening of anti-dengue activity in methanolic extracts of medicinal plants.
  Tang LI, Ling AP, Koh RY, Chye SM, Voon KG.BMC Complement Altern Med. 2012 Jan 13;12:3. doi: 10.1186/1472-6882-12-3.
• 20. Mosquito adulticidal and repellent activities of botanical extracts against malarial vector, Anopheles stephensi Liston (Diptera: Culicidae).
  Govindarajan M, Sivakumar R.Asian Pac J Trop Med. 2011 Dec;4(12):941-7. doi: 10.1016/S1995-7645(11)60223-X.

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