Botanical Ingredient

beta-Sitosterol Safety Tips

Handling of beta-Sitosterol should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. [Chemical constituents from Astilbe myriantha].
  Zou Y, Cui Y.Zhong Yao Cai. 2012 Jul;35(7):1095-7. Chinese.
• 2. β-Sitosterol oxidation products attenuate vasorelaxation by increasing reactive oxygen species and cyclooxygenase-2.
  Yang C, Chen ZY, Wong SL, Liu J, Liang YT, Lau CW, Lee HK, Huang Y, Tsang SY.Cardiovasc Res. 2012 Dec 17. [Epub ahead of print]
• 3. [Chemical constituents of the roots of Vaccinium bracteatum].
  Lv XL, Mai X, Guo H, Lai XP.Zhong Yao Cai. 2012 Jun;35(6):917-9. Chinese.
• 4. [Chemical constituents of Pilea cavaleriei subsp. cavaleriei].
  Ren HC, Qin RD, Zhang QY, Cheng W, Liang H.Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2581-4. Chinese.
• 5. [A new natural product from root of Angelica dahurica cv. Qibaizhi].
  Zhao A, Yang X, Yang X, Liu J, Wang Q, Wang W.Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2400-7. Chinese.
• 6. [Preliminary research of quality standard on Brassica rapa].
  Sun Y, Ma X, Tian S, Zhang F.Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2356-9. Chinese.
• 7. Antioxidant activities and triterpenoids isolated from Alternanthera brasiliana (L.) Kuntze leaves.
  Pereira DF, Zanon RB, Dos Santos M, Boligon AA, Athayde ML.Nat Prod Res. 2012 Dec 11. [Epub ahead of print]
• 8. Incorporation of β-sitosterol into mitochondrial membrane enhances mitochondrial function by promoting inner mitochondrial membrane fluidity.
  Shi C, Wu F, Xu J.J Bioenerg Biomembr. 2012 Dec 8. [Epub ahead of print]
• 9. Acute effect of β-sitosterol on calcium uptake mediates anti-inflammatory effect in murine activated neutrophils.
  Liz R, Zanatta L, Dos Reis GO, Horst H, Pizzolatti MG, Silva FR, Fröde TS.J Pharm Pharmacol. 2013 Jan;65(1):115-22. doi: 10.1111/j.2042-7158.2012.01568.x. Epub 2012 Oct 11.
• 10. [Chemical constituents of Pileostegia viburnoides var. glabrescens].
  Zou JY, Chen SH, Li QW, Ou YW, Chen HJ, Wang W.Zhong Yao Cai. 2012 May;35(5):724-5. Chinese.
• 11. Preparation of nano/submicrometer yam and its benefits on collagen secretion from skin fibroblast cells.
  Chiang LH, Chen SH, Yeh AI.J Agric Food Chem. 2012 Dec 19;60(50):12332-40. doi: 10.1021/jf304036c. Epub 2012 Dec 11.
• 12. Nutrition and benign prostatic hyperplasia.
  Espinosa G.Curr Opin Urol. 2013 Jan;23(1):38-41. doi: 10.1097/MOU.0b013e32835abd05.
• 13. [A new cardiac glycoside from Periploca forrestii].
  Xu R, Du J, Deng L, Yang F, Zhang J, Wang D, Zhang Y.Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(15):2286-8. Chinese.
• 14. Preclinical evaluation of hypoglycemic activity of Ipomoea digitata tuber in streptozotocin-induced diabetic rats.
  Pandey AK, Gupta PP, Lal VK.J Basic Clin Physiol Pharmacol. 2012 Nov 23:1-5. doi: 10.1515/jbcpp-2012-0042. [Epub ahead of print]
• 15. Sugar availability modulates polyisoprenoid and phytosterol profiles in Arabidopsis thaliana hairy root culture.
  Jozwiak A, Ples M, Skorupinska-Tudek K, Kania M, Dydak M, Danikiewicz W, Swiezewska E.Biochim Biophys Acta. 2012 Nov 22;1831(2):438-447. doi: 10.1016/j.bbalip.2012.11.006. [Epub ahead of print]
• 16. [Phytotherapy of benign prostate syndrome and prostate cancer :  Better than placebo].
  Wehrberger C, Dreikorn K, Schmitz-Dräger BJ, Oelke M, Madersbacher S.Urologe A. 2012 Dec;51(12):1674-82. doi: 10.1007/s00120-012-3033-0. German.
• 17. Flavonoids bearing an O-arabinofuranosyl-(1–>3)-rhamnoside moiety from Cladocolea micrantha: inhibitory effect on human melanoma cells.
  Guimarães AC, Magalhães A, Nakamura MJ, Siani AC, Barja-Fidalgo C, Sampaio AL.Nat Prod Commun. 2012 Oct;7(10):1311-4.
• 18. Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells.
  Eid SY, El-Readi MZ, Wink M.Phytomedicine. 2012 Nov 15;19(14):1288-97. doi: 10.1016/j.phymed.2012.08.010. Epub 2012 Nov 10.
• 19. Pomegranate phytosterol (β-sitosterol) and polyphenolic antioxidant (punicalagin) addition to statin, significantly protected against macrophage foam cells formation.
  Rosenblat M, Volkova N, Aviram M.Atherosclerosis. 2012 Oct 31. doi:pii: S0021-9150(12)00740-X.  10.1016/j.atherosclerosis.2012.10.054. [Epub ahead of print]
• 20. Dietary Aloe vera components’ effects on cholesterol lowering and estrogenic responses in juvenile goldfish, Carassius auratus.
  Palermo FA, Cocci P, Angeletti M, Felici A, Polzonetti-Magni AM, Mosconi G.Fish Physiol Biochem. 2012 Nov 8. [Epub ahead of print]