Botanical Ingredient

Camptothecin Safety Tips

Handling of Camptothecin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

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• 8. Enzyme-Responsive Silica Mesoporous Supports Capped with Azopyridinium Salts for Controlled Delivery Applications.
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• 10. Liposomal formulations of poorly soluble camptothecin: drug retention and biodistribution.
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• 11. Induction of p53, p21 and apoptosis by silencing the NF90/NF45 complex in human papilloma virus-transformed cervical carcinoma cells.
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• 12. Antibody-Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs.
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• 14. CK2-Mediated Hyperphosphorylation of Topoisomerase I Targets Serine 506, Enhances Topoisomerase I-DNA Binding, and Increases Cellular Camptothecin Sensitivity.
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• 15. Folic Acid-Modified Mesoporous Silica Nanoparticles for Cellular and Nuclear Targeted Drug Delivery.
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• 16. Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells.
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• 17. CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.
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• 18. Analysis of Type of Cell Death Induced by Topoisomerase Inhibitor SN-38 in Human Oral Squamous Cell Carcinoma Cell Lines.
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• 20. Magnetic field activated lipid-polymer hybrid nanoparticles for stimuli-responsive drug release.
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