Standard Herbal Extract

Elderberry Extract Safety Tips

Handling of Elderberry Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial.
  Jawad M, Schoop R, Suter A, Klein P, Eccles R.Evid Based Complement Alternat Med. 2012;2012:841315. Epub 2012 Sep 16.
• 2. In vitro inhibition of Eimeria tenella invasion of epithelial cells by phytochemicals.
  Burt SA, Tersteeg-Zijderveld MH, Jongerius-Gortemaker BG, Vervelde L, Vernooij JC.Vet Parasitol. 2013 Jan 31;191(3-4):374-8. doi: 10.1016/j.vetpar.2012.09.001. Epub 2012 Sep 7.
• 3. Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis.
  Tsai YL, Chiu CC, Yi-Fu Chen J, Chan KC, Lin SD.J Ethnopharmacol. 2012 Oct 11;143(3):914-9. doi: 10.1016/j.jep.2012.08.032. Epub 2012 Sep 1.
• 4. Treatment of the common cold in children and adults.
  Fashner J, Ericson K, Werner S.Am Fam Physician. 2012 Jul 15;86(2):153-9. Review.
• 5. Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients.
  Moltó J, Valle M, Miranda C, Cedeño S, Negredo E, Clotet B.Antimicrob Agents Chemother. 2012 Oct;56(10):5328-31. doi: 10.1128/AAC.01205-12. Epub 2012 Aug 6.
• 6. The bioanalysis of the major Echinacea purpurea constituents dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human plasma using LC-MS/MS.
  Goey AK, Rosing H, Meijerman I, Sparidans RW, Schellens JH, Beijnen JH.J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Aug 1;902:151-6. doi: 10.1016/j.jchromb.2012.06.022. Epub 2012 Jun 26.
• 7. Use of a standardized extract from Echinacea angustifolia (Polinacea) for the prevention of respiratory tract infections.
  Di Pierro F, Rapacioli G, Ferrara T, Togni S.Altern Med Rev. 2012 Mar;17(1):36-41.
• 8. Effect of an herbal mouth rinse in preventing periodontal inflammation in an experimental gingivitis model: a pilot study.
  Samuels N, Grbic JT, Saffer AJ, Wexler ID, Williams RC.Compend Contin Educ Dent. 2012 Mar;33(3):204-6, 208-11.
• 9. The Anxiolytic Potential and Psychotropic Side Effects of an Echinacea Preparation in Laboratory Animals and Healthy Volunteers.
  Haller J, Freund TF, Pelczer KG, Füredi J, Krecsak L, Zámbori J.Phytother Res. 2012 Mar 26. doi: 10.1002/ptr.4677. [Epub ahead of print]
• 10. Randomised, double blind, placebo-controlled trial of echinacea supplementation in air travellers.
  Tiralongo E, Lea RA, Wee SS, Hanna MM, Griffiths LR.Evid Based Complement Alternat Med. 2012;2012:417267. doi: 10.1155/2012/417267. Epub 2011 Dec 20.
• 11. The effectiveness of Echinacea extract or composite glucosamine, chondroitin and methyl sulfonyl methane supplements on acute and chronic rheumatoid arthritis rat model.
  Arafa NM, Hamuda HM, Melek ST, Darwish SK.Toxicol Ind Health. 2011 Dec 15. [Epub ahead of print]
• 12. Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension.
  Brown PN, Chan M, Paley L, Betz JM.J AOAC Int. 2011 Sep-Oct;94(5):1400-10.
• 13. Neuroprotective effects of a new skin care formulation following ultraviolet exposure.
  Fonseca BL, dos Santos BC, Martins P, Bonorino C, Corte TW, da Silva VD, Bauer ME.Cell Prolif. 2012 Feb;45(1):48-52. doi: 10.1111/j.1365-2184.2011.00795.x. Epub 2011 Dec 13.
• 14. Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases.
  Hudson JB.J Biomed Biotechnol. 2012;2012:769896. doi: 10.1155/2012/769896. Epub 2011 Oct 26. Review.
• 15. Evaluating the efficacy of cinnamaldehyde and Echinacea purpurea plant extract in broilers against Eimeria acervulina.
  Orengo J, Buendía AJ, Ruiz-Ibáñez MR, Madrid J, Del Río L, Catalá-Gregori P, García V, Hernández F.Vet Parasitol. 2012 Apr 30;185(2-4):158-63. doi: 10.1016/j.vetpar.2011.09.024. Epub 2011 Sep 22.
• 16. Effects of chemically characterized fractions from aerial parts of Echinacea purpurea and E. angustifolia on myelopoiesis in rats.
  Ramasahayam S, Baraka HN, Abdel Bar FM, Abuasal BS, Widrlechner MP, Sayed KA, Meyer SA.Planta Med. 2011 Nov;77(17):1883-9. doi: 10.1055/s-0031-1279990. Epub 2011 Aug 25.
• 17. Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors.
  Hohmann J, Rédei D, Forgo P, Szabó P, Freund TF, Haller J, Bojnik E, Benyhe S.Phytochemistry. 2011 Oct;72(14-15):1848-53. doi: 10.1016/j.phytochem.2011.06.008. Epub 2011 Jul 19.
• 18. Effects of Echinaforce® treatment on ex vivo-stimulated blood cells.
  Ritchie MR, Gertsch J, Klein P, Schoop R.Phytomedicine. 2011 Jul 15;18(10):826-31. doi: 10.1016/j.phymed.2011.05.011.
• 19. Dose-dependent in vivo effect of Rhodiola and Echinacea on the mitogen-induced lymphocyte proliferation in mice.
  Skopinska-Rózewska E, Sokolnicka I, Siwicki AK, Stankiewicz W, Dabrowski MP, Buchwald W, Krajewska-Patan A, Mielcarek S, M?cisz A, Furmanowa M.Pol J Vet Sci. 2011;14(2):265-72.
• 20. The effects of an Echinacea preparation on synaptic transmission and the firing properties of CA1 pyramidal cells in the hippocampus.
  Hájos N, Holderith N, Németh B, Papp OI, Szabó GG, Zemankovics R, Freund TF, Haller J.Phytother Res. 2012 Mar;26(3):354-62. doi: 10.1002/ptr.3556. Epub 2011 Jun 30.

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