Standard Herbal Extract

Feverfew Extract Safety Tips

Handling of Feverfew Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Characterization and identification of steroidal saponins from the seeds of Trigonella foenum-graecum by ultra high-performance liquid chromatography and hybrid time-of-flight mass spectrometry.
  Kang LP, Zhao Y, Pang X, Yu HS, Xiong CQ, Zhang J, Gao Y, Yu K, Liu C, Ma BP.J Pharm Biomed Anal. 2013 Feb 23;74:257-67. doi: 10.1016/j.jpba.2012.11.005. Epub 2012 Nov 10.
• 2. Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells.
  Al-Daghri NM, Alokail MS, Alkharfy KM, Mohammed AK, Abd-Alrahman SH, Yakout SM, Amer OE, Krishnaswamy S.BMC Complement Altern Med. 2012 Oct 30;12:202. doi: 10.1186/1472-6882-12-202.
• 3. Antiallergic effect of Trigonella foenum-graecum L. extracts on allergic skin inflammation induced by trimellitic anhydride in BALB/c mice.
  Bae MJ, Shin HS, Choi DW, Shon DH.J Ethnopharmacol. 2012 Dec 18;144(3):514-22. doi: 10.1016/j.jep.2012.09.030. Epub 2012 Oct 2.
• 4. Green synthesis of gold nanoparticles using Trigonella foenum-graecum and its size-dependent catalytic activity.
  Aswathy Aromal S, Philip D.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov;97:1-5. doi: 10.1016/j.saa.2012.05.083. Epub 2012 Jun 6.
• 5. Preventive and curative effect of Trigonella foenum-graecum L. seeds in C57BL/6J models of type 2 diabetes induced by high-fat diet.
  Hamza N, Berke B, Cheze C, Le Garrec R, Umar A, Agli AN, Lassalle R, Jové J, Gin H, Moore N.J Ethnopharmacol. 2012 Jul 13;142(2):516-22. doi: 10.1016/j.jep.2012.05.028. Epub 2012 May 23.
• 6. Ameliorative effects of standardized extract from Trigonella foenum-graecum L. seeds on painful peripheral neuropathy in rats.
  Morani AS, Bodhankar SL, Mohan V, Thakurdesai PA.Asian Pac J Trop Med. 2012 May;5(5):385-90. doi: 10.1016/S1995-7645(12)60064-9.
• 7. Alkaloid and flavonoid rich fractions of fenugreek seeds (Trigonella foenum-graecum L.) with antinociceptive and anti-inflammatory effects.
  Mandegary A, Pournamdari M, Sharififar F, Pournourmohammadi S, Fardiar R, Shooli S.Food Chem Toxicol. 2012 Jul;50(7):2503-7. doi: 10.1016/j.fct.2012.04.020. Epub 2012 Apr 20.
• 8. Effect of ethanol extract of Trigonella foenum graecum (Fenugreek) seeds on Freund’s adjuvant-induced arthritis in albino rats.
  Suresh P, Kavitha ChN, Babu SM, Reddy VP, Latha AK.Inflammation. 2012 Aug;35(4):1314-21. doi: 10.1007/s10753-012-9444-7.
• 9. Study of lipid profile and parieto-temporal lipid peroxidation in AlCl? mediated neurotoxicity. Modulatory effect of fenugreek seeds.
  Belaïd-Nouira Y, Bakhta H, Bouaziz M, Flehi-Slim I, Haouas Z, Ben Cheikh H.Lipids Health Dis. 2012 Jan 26;11:16. doi: 10.1186/1476-511X-11-16.
• 10. The developmental neurobehavioral effects of fenugreek seeds on prenatally exposed mice.
  Khalki L, Bennis M, Sokar Z, Ba-M’hamed S.J Ethnopharmacol. 2012 Jan 31;139(2):672-7. doi: 10.1016/j.jep.2011.12.011. Epub 2011 Dec 13.
• 11. Effect of fenugreek seed extract on adriamycin-induced hepatotoxicity and oxidative stress in albino rats.
  Sakr SA, Abo-El-Yazid SM.Toxicol Ind Health. 2012 Nov;28(10):876-85. doi: 10.1177/0748233711425076. Epub 2011 Nov 14.
• 12. Aqueous fenugreek seed extract ameliorates adriamycin-induced cytotoxicity and testicular alterations in albino rats.
  Sakr SA, El-Shenawy SM, Al-Shabka AM.Reprod Sci. 2012 Jan;19(1):70-80. doi: 10.1177/1933719111413301. Epub 2011 Nov 3.
• 13. Effect of fenugreek seeds extract on cyclophosphamide-induced histomorphometrical, ultrastructural and biochemical changes in testes of albino mice.
  Sakr SA, Mahran HA, Abo-El-Yazid SM.Toxicol Ind Health. 2012 Apr;28(3):276-88. doi: 10.1177/0748233711412427. Epub 2011 Sep 23.
• 14. Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts.
  Yasuda M, Wilson DR, Fugmann SD, Moaddel R.Anal Chem. 2011 Oct 1;83(19):7400-7. doi: 10.1021/ac201403y. Epub 2011 Sep 2.
• 15. Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity.
  Xue W, Lei J, Li X, Zhang R.Nutr Res. 2011 Jul;31(7):555-62. doi: 10.1016/j.nutres.2011.05.010.
• 16. Anaphylactic reactions in mice with Fenugreek allergy.
  Vinje NE, Namork E, Løvik M.Scand J Immunol. 2011 Oct;74(4):342-53. doi: 10.1111/j.1365-3083.2011.02587.x.
• 17. Protective role of Trigonella foenum graceum extract against oxidative stress in hyperglycemic rats.
  Middha SK, Bhattacharjee B, Saini D, Baliga MS, Nagaveni MB, Usha T.Eur Rev Med Pharmacol Sci. 2011 Apr;15(4):427-35.
• 18. Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum-graecum Extract and Mineral Formulation.
  Steels E, Rao A, Vitetta L.Phytother Res. 2011 Feb 10. doi: 10.1002/ptr.3360. [Epub ahead of print]
• 19. Fenugreek supplementation imparts erythrocyte resistance to cypermethrin induced oxidative changes in vivo.
  Navayath S, Thiyagarajan D.J Complement Integr Med. 2011 Jan;8(1). doi: 10.2202/1553-3840.1436.
• 20. Anti-hyperglycemic and anti-oxidative effect of aqueous extract of Momordica charantia pulp and Trigonella foenum graecum seed in alloxan-induced diabetic rats.
  Tripathi UN, Chandra D.Indian J Biochem Biophys. 2010 Aug;47(4):227-33.