Standard Herbal Extract

Honeysuckle Flower Extract Safety Tips

Handling of Honeysuckle Flower Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Evaluation of the wound-healing activity of Hibiscus rosa sinensis L (Malvaceae) in Wistar albino rats.
  Bhaskar A, Nithya V.Indian J Pharmacol. 2012 Nov;44(6):694-8. doi: 10.4103/0253-7613.103252.
• 2. Antidepressant-like activity of anthocyanidins from Hibiscus rosa-sinensis flowers in tail suspension test and forced swim test.
  Shewale PB, Patil RA, Hiray YA.Indian J Pharmacol. 2012 Jul-Aug;44(4):454-7. doi: 10.4103/0253-7613.99303.
• 3. Long-term ingestion of Hibiscus sabdariffa calyx extract enhances myocardial capillarization in the spontaneously hypertensive rat.
  Inuwa I, Ali BH, Al-Lawati I, Beegam S, Ziada A, Blunden G.Exp Biol Med (Maywood). 2012 May 1;237(5):563-9. doi: 10.1258/ebm.2012.011357.
• 4. Antidepressant-like effects of methanol extract of Hibiscus tiliaceus flowers in mice.
  Vanzella C, Bianchetti P, Sbaraini S, Vanzin SI, Melecchi MI, Caramão EB, Siqueira IR.BMC Complement Altern Med. 2012 Apr 12;12:41. doi: 10.1186/1472-6882-12-41.
• 5. Adsorption and desorption properties of macroporous resins for anthocyanins from the calyx extract of roselle (Hibiscus sabdariffa L.).
  Chang XL, Wang D, Chen BY, Feng YM, Wen SH, Zhan PY.J Agric Food Chem. 2012 Mar 7;60(9):2368-76. doi: 10.1021/jf205311v. Epub 2012 Feb 23.
• 6. Polyphenolic compounds from flowers of Hibiscus rosa-sinensis Linn. and their inhibitory effect on alkaline phosphatase enzyme activity in vitro.
  Salib JY, Daniel EN, Hifnawy MS, Azzam SM, Shaheed IB, Abdel-Latif SM.Z Naturforsch C. 2011 Sep-Oct;66(9-10):453-9.
• 7. Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract.
  Alarcón-Alonso J, Zamilpa A, Aguilar FA, Herrera-Ruiz M, Tortoriello J, Jimenez-Ferrer E.J Ethnopharmacol. 2012 Feb 15;139(3):751-6. doi: 10.1016/j.jep.2011.12.005. Epub 2011 Dec 13.
• 8. Effect of extract of Hibiscus on the ultrastructure of the testis in adult mice.
  Mahmoud YI.Acta Histochem. 2012 Jul;114(4):342-8. doi: 10.1016/j.acthis.2011.07.002. Epub 2011 Jul 27.
• 9. Determination of antimicrobial activity of sorrel (Hibiscus sabdariffa) on Escherichia coli O157:H7 isolated from food, veterinary, and clinical samples.
  Fullerton M, Khatiwada J, Johnson JU, Davis S, Williams LL.J Med Food. 2011 Sep;14(9):950-6. doi: 10.1089/jmf.2010.0200. Epub 2011 May 6.
• 10. Hot and cold water infusion aroma profiles of Hibiscus sabdariffa: fresh compared with dried.
  Ramírez-Rodrigues MM, Balaban MO, Marshall MR, Rouseff RL.J Food Sci. 2011 Mar;76(2):C212-7. doi: 10.1111/j.1750-3841.2010.01989.x. Epub 2011 Feb 1.
• 11. Liposome-containing Hibiscus sabdariffa calyx extract formulations with increased antioxidant activity, improved dermal penetration and reduced dermal toxicity.
  Pinsuwan S, Amnuaikit T, Ungphaiboon S, Itharat A.J Med Assoc Thai. 2010 Dec;93 Suppl 7:S216-26.
• 12. Hibiscus sabdariffa ethanolic extract protects against dyslipidemia and oxidative stress induced by chronic cholesterol administration in rabbits.
  Ekor M, Adesanoye OA, Udo IE, Adegoke OA, Raji J, Farombi EO.Afr J Med Med Sci. 2010 Dec;39 Suppl:161-70.
• 13. Aqueous extract of Hibiscus sabdariffa L. decelerates acetaminophen-induced acute liver damage by reducing cell death and oxidative stress in mouse experimental models.
  Liu LC, Wang CJ, Lee CC, Su SC, Chen HL, Hsu JD, Lee HJ.J Sci Food Agric. 2010 Jan 30;90(2):329-37. doi: 10.1002/jsfa.3821.
• 14. Antimutagenicity of some flowers grown in Thailand.
  Wongwattanasathien O, Kangsadalampai K, Tongyonk L.Food Chem Toxicol. 2010 Apr;48(4):1045-51. doi: 10.1016/j.fct.2010.01.018. Epub 2010 Jan 25.
• 15. Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa.
  Ojeda D, Jiménez-Ferrer E, Zamilpa A, Herrera-Arellano A, Tortoriello J, Alvarez L.J Ethnopharmacol. 2010 Jan 8;127(1):7-10. doi: 10.1016/j.jep.2009.09.059. Epub 2009 Oct 4.
• 16. The aqueous extract of Hibiscus sabdariffa calices modulates the production of monocyte chemoattractant protein-1 in humans.
  Beltrán-Debón R, Alonso-Villaverde C, Aragonès G, Rodríguez-Medina I, Rull A, Micol V, Segura-Carretero A, Fernández-Gutiérrez A, Camps J, Joven J.Phytomedicine. 2010 Mar;17(3-4):186-91. doi: 10.1016/j.phymed.2009.08.006. Epub 2009 Sep 17.
• 17. Effect of Hibiscus sabdariffa L. dried calyx ethanol extract on fat absorption-excretion, and body weight implication in rats.
  Carvajal-Zarrabal O, Hayward-Jones PM, Orta-Flores Z, Nolasco-Hipólito C, Barradas-Dermitz DM, Aguilar-Uscanga MG, Pedroza-Hernández MF.J Biomed Biotechnol. 2009;2009:394592. doi: 10.1155/2009/394592. Epub 2009 Sep 10.
• 18. Antioxidant and antihyperlipidemic activity of Hibiscus sabdariffa Linn. leaves and calyces extracts in rats.
  Ochani PC, D’Mello P.Indian J Exp Biol. 2009 Apr;47(4):276-82.
• 19. Anti-Campylobacter, anti-aerobic, and anti-oxidative effects of roselle calyx extract and protocatechuic acid in ground beef.
  Yin MC, Chao CY.Int J Food Microbiol. 2008 Sep 30;127(1-2):73-7. doi: 10.1016/j.ijfoodmicro.2008.06.002. Epub 2008 Jun 13.
• 20. Effect of Hibiscus anthocyanins-rich extract induces apoptosis of proliferating smooth muscle cell via activation of P38 MAPK and p53 pathway.
  Lo CW, Huang HP, Lin HM, Chien CT, Wang CJ.Mol Nutr Food Res. 2007 Dec;51(12):1452-60.

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