Botanical Ingredient

References

• 1. [The relationship between the quality and the leaf shape of magnolia officinalis produced in Hubei enshi].
  Yang HB, Shi L, Yu JJ, Li MM.Zhong Yao Cai. 2012 Jul;35(7):1036-9. Chinese.
• 2. Honokiol protects rat hearts against myocardial ischemia reperfusion injury by reducing oxidative stress and inflammation.
  Wang Y, Zhang ZZ, Wu Y, Zhan J, He XH, Wang YL.Exp Ther Med. 2013 Jan;5(1):315-319. Epub 2012 Oct 25.
• 3. Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death.
  Tian W, Deng Y, Li L, He H, Sun J, Xu D.Int J Oncol. 2012 Dec 14. doi: 10.3892/ijo.2012.1739. [Epub ahead of print]
• 4. Honokiol induces cytotoxic and cytostatic effects in malignant melanoma cancer cells.
  Kaushik G, Ramalingam S, Subramaniam D, Rangarajan P, Protti P, Rammamoorthy P, Anant S, Mammen JM.Am J Surg. 2012 Dec;204(6):868-73. doi: 10.1016/j.amjsurg.2012.09.001.
• 5. Inhibition of class I histone deacetylases in non-small cell lung cancer by honokiol leads to suppression of cancer cell growth and induction of cell death in vitro and in vivo.
  Singh T, Prasad R, Katiyar SK.Epigenetics. 2012 Dec 5;8(1). [Epub ahead of print]
• 6. Comparative Inhibitory Effects of Magnolol, Honokiol, Eugenol and bis-Eugenol on Cyclooxygenase-2 Expression and Nuclear Factor-Kappa B Activation in RAW264.7 Macrophage-like Cells Stimulated with Fimbriae of Porphyromonas gingivalis.
  Murakami Y, Kawata A, Seki Y, Koh T, Yuhara K, Maruyama T, Machino M, Ito S, Kadoma Y, Fujisawa S.In Vivo. 2012 Nov;26(6):941-50.
• 7. Honokiol protects brain against ischemia-reperfusion injury in rats through disrupting PSD95-nNOS interaction.
  Hu Z, Bian X, Liu X, Zhu Y, Zhang X, Chen S, Wang K, Wang Y.Brain Res. 2012 Nov 10. doi:pii: S0006-8993(12)01779-9.  10.1016/j.brainres.2012.11.004. [Epub ahead of print]
• 8. Honokiol, a multifunctional tumor cell death inducer.
  Tian W, Xu D, Deng YC.Pharmazie. 2012 Oct;67(10):811-6. Review.
• 9. Study on Spectrum-Effect Relationship of Rhizoma Rhei, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus and their Formula.
  Xie RF, Zhou X, Shi ZN, Li YM, Li ZC.J Chromatogr Sci. 2012 Oct 31. [Epub ahead of print]
• 10. Modulation of P-glycoprotein expression by honokiol, magnolol and 4-O-methylhonokiol, the bioactive components of Magnolia officinalis.
  Han HK, Van Anh LT.Anticancer Res. 2012 Oct;32(10):4445-52.
• 11. Modulating testosterone pathway: a new strategy to tackle male skin aging?
  Bernard P, Scior T, Do QT.Clin Interv Aging. 2012;7:351-61. doi: 10.2147/CIA.S34034. Epub 2012 Sep 13.
• 12. Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice.
  Liu SH, Wang KB, Lan KH, Lee WJ, Pan HC, Wu SM, Peng YC, Chen YC, Shen CC, Cheng HC, Liao KK, Sheu ML.PLoS One. 2012;7(8):e43711. doi: 10.1371/journal.pone.0043711. Epub 2012 Aug 24.
• 13. Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction () in rats.
  Gong HL, Tang WF, Wang J, Chen GY, Huang X.Chin J Integr Med. 2012 Sep;18(9):708-13. doi: 10.1007/s11655-012-1205-9. Epub 2012 Aug 31.
• 14. Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules.
  Jeong JJ, Lee JH, Chang KC, Kim HJ.Int J Oncol. 2012 Aug 7. doi: 10.3892/ijo.2012.1582. [Epub ahead of print]
• 15. Time and dose-response effects of honokiol on UVB-induced skin cancer development.
  Guillermo RF, Chilampalli C, Zhang X, Zeman D, Fahmy H, Dwivedi C.Drug Discov Ther. 2012 Jun;6(3):140-6.
• 16. Honokiol inhibits vascular vessel formation of mouse embryonic stem cell-derived endothelial cells via the suppression of PECAM and MAPK/mTOR signaling pathway.
  Kim GD, Bae SY, Park HJ, Bae K, Lee SK.Cell Physiol Biochem. 2012;30(3):758-70. doi: 10.1159/000341455. Epub 2012 Aug 2.
• 17. Synergistic antitumor effects of liposomal honokiol combined with cisplatin in colon cancer models.
  Cheng N, Xia T, Han Y, He QJ, Zhao R, Ma JR.Oncol Lett. 2011 Sep 1;2(5):957-962. Epub 2011 Jul 5.
• 18. Honokiol: a novel natural agent for cancer prevention and therapy.
  Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP.Curr Mol Med. 2012 Jul 23. [Epub ahead of print]
• 19. [Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines].
  Shan QQ, Gong YP, Guo Y, Lin J, Zhou RQ, Yang X.Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 May;43(3):362-6. Chinese.
• 20. Design, synthesis, and anti-proliferative evaluation of [1,1′-biphenyl]-4-ols as inhibitor of HUVEC migration and tube formation.
  Ran Y, Ma L, Wang X, Chen J, Wang G, Peng A, Chen L.Molecules. 2012 Jul 5;17(7):8091-104. doi: 10.3390/molecules17078091.