Standard Herbal Extract

Hops Flower Extract Safety Tips

Handling of Hops Flower Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Prophylactic effects of Lonicera japonica extract on dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response.
  Park JW, Bae H, Lee G, Hong BG, Yoo HH, Lim SJ, Lee K, Kim J, Ryu B, Lee BJ, Bae J, Lee H, Bu Y.Br J Nutr. 2012 May 9:1-10. [Epub ahead of print]
• 2. Neuroprotective activity of the methanolic extract of Lonicera japonica in glutamate-injured primary rat cortical cells.
  Weon JB, Yang HJ, Lee B, Yun BR, Ahn JH, Lee HY, Ma CJ.Pharmacogn Mag. 2011 Oct;7(28):284-8. doi: 10.4103/0973-1296.90404.
• 3. [Study on constituents of essential oil from Lonicera fulvotomentosa in different collected periods].
  Huang L, Wang D, Chen X.Zhongguo Zhong Yao Za Zhi. 2011 Aug;36(16):2230-2. Chinese.
• 4. Standardised herbal extract of chlorogenic acid from leaves of Etlingera elatior (Zingiberaceae).
  Chan EW, Lim YY, Tan SP.Pharmacognosy Res. 2011 Jul;3(3):178-84. doi: 10.4103/0974-8490.85003.
• 5. Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica.
  Oku H, Ogawa Y, Iwaoka E, Ishiguro K.Biol Pharm Bull. 2011;34(8):1330-3.
• 6. Simultaneous quantification of Echinacea species, Flos Lonicerae, Radix Scutellaria and Fructus Forsythiae combinations by rapid resolution liquid chromatography.
  Ma J, Ma YC, Cai C, Wang D, Hou FF, Luo M, Lu S, Gorecki DC, Patel AV, Chen A, Jin P.Nat Prod Commun. 2011 May;6(5):639-43.
• 7. [Studies on chemical constituents of the extract of Lonicera japonica].
  Chen QZ, Lin RC, Wang GL, Li FM.Zhong Yao Cai. 2010 Jun;33(6):920-2. Chinese.
• 8. Screening of permeable compounds in Flos Lonicerae Japonicae with liposome using ultrafiltration and HPLC.
  Chen X, Xia Y, Lu Y, Liang J.J Pharm Biomed Anal. 2011 Jan 25;54(2):406-10. doi: 10.1016/j.jpba.2010.08.028. Epub 2010 Sep 28.
• 9. Metabonomics study of the protective effects of Lonicera japonica extract on acute liver injury in dimethylnitrosamine treated rats.
  Sun C, Teng Y, Li G, Yoshioka S, Yokota J, Miyamura M, Fang H, Zhang Y.J Pharm Biomed Anal. 2010 Sep 21;53(1):98-102. doi: 10.1016/j.jpba.2010.03.015. Epub 2010 Mar 17.
• 10. Protective effects of Flos lonicera extract on acute liver injury by dimethylnitrosamine-induced in rats.
  Teng Y, Sun CH, Li G, Sun G, Nomachi Y, Yokota J, Yoshioka S, Gang J, Jiao S, Zhang Y, Miyamura M.J Nat Med. 2010 Jul;64(3):288-94. doi: 10.1007/s11418-010-0405-x. Epub 2010 Mar 20.
• 11. Composition of diethyl ether flower extracts of Lonicera fragrantissima Lindl. & Paxton (caprifoliaceae).
  Radulovi? N, Blagojevi? P, Pali? R.Nat Prod Commun. 2009 Nov;4(11):1581-4.
• 12. Structural characterization and identification of iridoid glycosides, saponins, phenolic acids and flavonoids in Flos Lonicerae Japonicae by a fast liquid chromatography method with diode-array detection and time-of-flight mass spectrometry.
  Qi LW, Chen CY, Li P.Rapid Commun Mass Spectrom. 2009 Oct;23(19):3227-42. doi: 10.1002/rcm.4245.
• 13. The structure and absolute configuration of Shuangkangsu: a novel natural cyclic peroxide from Lonicera japonica (Thunb.).
  Yu DQ, Chen RY, Huang LJ, Xie FZ, Ming DS, Zhou K, Li HY, Tong KM.J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):851-6. doi: 10.1080/10286020802144677.
• 14. [Studies on the chemical constituents of Lonicera macranthoides].
  Jia XD, Zhao XZ, Wang M, Dong YF, Feng X.Zhong Yao Cai. 2008 Jul;31(7):988-90. Chinese.
• 15. Rapid and simple method for screening of natural antioxidants from Chinese herb Flos Lonicerae Japonicae by DPPH-HPLC-DAD-TOF/MS.
  Tang D, Li HJ, Chen J, Guo CW, Li P.J Sep Sci. 2008 Oct;31(20):3519-26. doi: 10.1002/jssc.200800173.
• 16. Anti-angiogenic, antinociceptive and anti-inflammatory activities of Lonicera japonica extract.
  Yoo HJ, Kang HJ, Song YS, Park EH, Lim CJ.J Pharm Pharmacol. 2008 Jun;60(6):779-86. doi: 10.1211/jpp.60.6.0014.
• 17. pH-gradient counter-current chromatography isolation of natural antioxidant chlorogenic acid from Lonicera japonica Thumb. using an upright coil planet centrifuge with three multi-layer coils connected in series.
  Wang T, Jiang X, Yang L, Wu S.J Chromatogr A. 2008 Feb 8;1180(1-2):53-8. Epub 2007 Dec 8.
• 18. Characterization of antioxidant activity of extracts from Flos Lonicerae.
  Lan W, Zhaojun Z, Zesheng Z.Drug Dev Ind Pharm. 2007 Aug;33(8):841-7.
• 19. Antioxidant constituents and a new triterpenoid glycoside from Flos Lonicerae.
  Choi CW, Jung HA, Kang SS, Choi JS.Arch Pharm Res. 2007 Jan;30(1):1-7.
• 20. Trifunctional inhibition of COX-2 by extracts of Lonicera japonica: direct inhibition, transcriptional and post-transcriptional down regulation.
  Xu Y, Oliverson BG, Simmons DL.J Ethnopharmacol. 2007 May 22;111(3):667-70. Epub 2007 Jan 19.

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