Standard Herbal Extract

Ligustrum Extract Safety Tips

Handling of Ligustrum Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. The antimicrobial effects of deglycyrrhizinated licorice root extract on Streptococcus mutans UA159 in both planktonic and biofilm cultures.
  Ahn SJ, Cho EJ, Kim HJ, Park SN, Lim YK, Kook JK.Anaerobe. 2012 Dec;18(6):590-6. doi: 10.1016/j.anaerobe.2012.10.005. Epub 2012 Oct 30.
• 2. Glycyrrhetinic acid inhibits Porphyromonas gingivalis lipopolysaccharide-induced vascular permeability via the suppression of interleukin-8.
  Kim SR, Jeon HJ, Park HJ, Kim MK, Choi WS, Jang HO, Bae SK, Jeong CH, Bae MK.Inflamm Res. 2012 Oct 13. [Epub ahead of print]
• 3. Liquorice reduced cyclosporine bioavailability by activating P-glycoprotein and CYP 3A.
  Hou YC, Lin SP, Chao PD.Food Chem. 2012 Dec 15;135(4):2307-12. doi: 10.1016/j.foodchem.2012.07.061. Epub 2012 Jul 20.
• 4. Chromolithic method development, validation, and system suitability analysis of ultra-sound assisted extraction of glycyrrhizic acid and glycyrrhetinic acid from Glycyrrhiza glabra.
  Gupta S, Sharma R, Pandotra P, Jaglan S, Gupta AP.Nat Prod Commun. 2012 Aug;7(8):991-4.
• 5. An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts.
  Knipping K, Garssen J, van’t Land B.Virol J. 2012 Jul 26;9:137. doi: 10.1186/1743-422X-9-137.
• 6. Inhibitory effects of Glycyrrhizae radix and its active component, isoliquiritigenin, on Aβ(25-35)-induced neurotoxicity in cultured rat cortical neurons.
  Lee HK, Yang EJ, Kim JY, Song KS, Seong YH.Arch Pharm Res. 2012 May;35(5):897-904. doi: 10.1007/s12272-012-0515-y. Epub 2012 May 29.
• 7. Therapeutic associated with occupational exposure to silica.
  Raghuvanshi S, Shrivastava S, Johri S, Shukla S.J Trace Elem Med Biol. 2012 Jun;26(2-3):205-9. doi: 10.1016/j.jtemb.2012.04.006. Epub 2012 May 8.
• 8. Licorice extract a sweet way to control decay.
  Reitz J.Pa Dent J (Harrisb). 2012 Jan-Feb;79(1):40-1. No abstract available.
• 9. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial.
  Hajiaghamohammadi AA, Ziaee A, Samimi R.Phytother Res. 2012 Sep;26(9):1381-4. doi: 10.1002/ptr.3728. Epub 2012 Feb 6.
• 10. In vitro antioxidant activity of extracts of Sybaris liquorice roots from Southern Italy.
  Gabriele B, Fazio A, Carchedi M, Plastina P.Nat Prod Res. 2012;26(23):2176-81. doi: 10.1080/14786419.2011.647022. Epub 2012 Jan 11.
• 11. Evaluation of antioxidant and urease inhibition activities of roots of Glycyrrhiza glabra.
  Lateef M, Iqbal L, Fatima N, Siddiqui K, Afza N, Zia-ul-Haq M, Ahmad M.Pak J Pharm Sci. 2012 Jan;25(1):99-102.
• 12. Interaction of glycyrrhizin and glycyrrhetinic acid with DNA.
  Nafisi S, Bonsaii M, Manouchehri F, Abdi K.DNA Cell Biol. 2012 Jan;31(1):114-21. doi: 10.1089/dna.2011.1287. Epub 2011 Nov 10.
• 13. Food components with anticaries activity.
  Gazzani G, Daglia M, Papetti A.Curr Opin Biotechnol. 2012 Apr;23(2):153-9. doi: 10.1016/j.copbio.2011.09.003. Epub 2011 Oct 24. Review.
• 14. Evaluation of the genotoxic potential of standardized extract of Glycyrrhiza glabra (GutGard™).
  Chandrasekaran CV, Sundarajan K, Gupta A, Srikanth HS, Edwin J, Agarwal A.Regul Toxicol Pharmacol. 2011 Dec;61(3):373-80. doi: 10.1016/j.yrtph.2011.10.002. Epub 2011 Oct 13.
• 15. Methyl jasmonate elicitation enhances glycyrrhizin production in Glycyrrhiza inflata hairy roots cultures.
  Wongwicha W, Tanaka H, Shoyama Y, Putalun W.Z Naturforsch C. 2011 Jul-Aug;66(7-8):423-8.
• 16. Intensified extraction of ionized natural products by ion pair centrifugal partition extraction.
  Hamzaoui M, Hubert J, Hadj-Salem J, Richard B, Harakat D, Marchal L, Foucault A, Lavaud C, Renault JH.J Chromatogr A. 2011 Aug 5;1218(31):5254-62. doi: 10.1016/j.chroma.2011.06.018. Epub 2011 Jun 17.
• 17. Isoliquiritigenin from licorice root suppressed neovascularisation in experimental ocular angiogenesis models.
  Jhanji V, Liu H, Law K, Lee VY, Huang SF, Pang CP, Yam GH.Br J Ophthalmol. 2011 Sep;95(9):1309-15. doi: 10.1136/bjophthalmol-2011-300110. Epub 2011 Jun 30.
• 18. Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra).
  Simons R, Vincken JP, Mol LA, The SA, Bovee TF, Luijendijk TJ, Verbruggen MA, Gruppen H.Anal Bioanal Chem. 2011 Jul;401(1):305-13. doi: 10.1007/s00216-011-5061-9. Epub 2011 May 15.
• 19. Protective effects of glycyrrhizin against β?-adrenergic receptor agonist-induced receptor internalization and cell apoptosis.
  Shi Q, Hou Y, Yang Y, Bai G.Biol Pharm Bull. 2011;34(5):609-17.
• 20. Ornithine decarboxylase prevents dibenzoylmethane-induced apoptosis through repressing reactive oxygen species generation.
  Wu CL, Liao YF, Hung YC, Lu KH, Hung HC, Liu GY.J Biochem Mol Toxicol. 2011 Sep-Oct;25(5):312-9. doi: 10.1002/jbt.20391. Epub 2011 Apr 26.

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