Standard Herbal Extract

Mango Leaf Extract Safety Tips

Handling of Mango Leaf Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Induction of a T-Helper 1 (Th1) Immune Response in Mice by an Extract from the Pleurotus eryngii (Eringi) Mushroom.
  Ike K, Kameyama N, Ito A, Imai S.J Med Food. 2012 Dec;15(12):1124-8. doi: 10.1089/jmf.2012.2239. Epub 2012 Nov 7.
• 2. Immune enhancing effects of WB365, a novel combination of Ashwagandha (Withania somnifera) and Maitake (Grifola frondosa) extracts.
  Vetvicka V, Vetvickova J.N Am J Med Sci. 2011 Jul;3(7):320-4. doi: 10.4297/najms.2011.3320.
• 3. Preparation, characterization, and biological properties of β-glucans.
  Rahar S, Swami G, Nagpal N, Nagpal MA, Singh GS.J Adv Pharm Technol Res. 2011 Apr;2(2):94-103. doi: 10.4103/2231-4040.82953.
• 4. Preparation of culinary-medicinal maitake mushroom, Grifola frondosa (Dicks.: Fr.) S.F. Gray (Aphyllophoromycetideae)-fermented wheat and its antioxidant properties.
  Huang SJ, Tsai SY, Lin SY, Liang CH, Lian PY, Mau JL.Int J Med Mushrooms. 2011;13(1):61-71.
• 5. Antioxidant properties and antioxidant compounds of various extracts from the edible basidiomycete Grifola frondosa (Maitake).
  Yeh JY, Hsieh LH, Wu KT, Tsai CF.Molecules. 2011 Apr 15;16(4):3197-211. doi: 10.3390/molecules16043197.
• 6. Maitake (D fraction) mushroom extract induces apoptosis in breast cancer cells by BAK-1 gene activation.
  Soares R, Meireles M, Rocha A, Pirraco A, Obiol D, Alonso E, Joos G, Balogh G.J Med Food. 2011 Jun;14(6):563-72. doi: 10.1089/jmf.2010.0095. Epub 2011 Apr 11.
• 7. Biological activities of Fructus arctii fermented with the basidiomycete Grifola frondosa.
  Kim JH, Bae JT, Song MH, Lee GS, Choe SY, Pyo HB.Arch Pharm Res. 2010 Dec;33(12):1943-51. doi: 10.1007/s12272-010-1209-y. Epub 2010 Dec 30.
• 8. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate.
  Chen JT, Tominaga K, Sato Y, Anzai H, Matsuoka R.J Altern Complement Med. 2010 Dec;16(12):1295-9. doi: 10.1089/acm.2009.0696. Epub 2010 Oct 29.
• 9. Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells.
  Martin KR, Brophy SK.Exp Biol Med (Maywood). 2010 Nov;235(11):1306-14. doi: 10.1258/ebm.2010.010113. Epub 2010 Oct 4.
• 10. Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.
  Lin H, de Stanchina E, Zhou XK, Hong F, Seidman A, Fornier M, Xiao WL, Kennelly EJ, Wesa K, Cassileth BR, Cunningham-Rundles S.Cancer Immunol Immunother. 2010 Jun;59(6):885-97. doi: 10.1007/s00262-009-0815-3. Epub 2010 Feb 6.
• 11. Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling.
  Lee JS, Park SY, Thapa D, Choi MK, Chung IM, Park YJ, Yong CS, Choi HG, Kim JA.Exp Mol Med. 2010 Feb 28;42(2):143-54. doi: 10.3858/emm.2010.42.2.016.
• 12. INR elevation with maitake extract in combination with warfarin.
  Hanselin MR, Vande Griend JP, Linnebur SA.Ann Pharmacother. 2010 Jan;44(1):223-4. doi: 10.1345/aph.1M510. Epub 2009 Dec 29. No abstract available.
• 13. Synergistic potentiation of interferon activity with maitake mushroom d-fraction on bladder cancer cells.
  Louie B, Rajamahanty S, Won J, Choudhury M, Konno S.BJU Int. 2010 Apr;105(7):1011-5. doi: 10.1111/j.1464-410X.2009.08870.x. Epub 2009 Sep 4.
• 14. Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines.
  Shomori K, Yamamoto M, Arifuku I, Teramachi K, Ito H.Oncol Rep. 2009 Sep;22(3):615-20.
• 15. An extract of the medicinal mushroom Agaricus blazei Murill can protect against allergy.
  Ellertsen LK, Hetland G.Clin Mol Allergy. 2009 May 5;7:6. doi: 10.1186/1476-7961-7-6.
• 16. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects.
  Deng G, Lin H, Seidman A, Fornier M, D’Andrea G, Wesa K, Yeung S, Cunningham-Rundles S, Vickers AJ, Cassileth B.J Cancer Res Clin Oncol. 2009 Sep;135(9):1215-21. doi: 10.1007/s00432-009-0562-z. Epub 2009 Mar 1.
• 17. Augmentation of sebaceous lipogenesis by an ethanol extract of Grifola frondosa (Maitake mushroom) in hamsters in vivo and in vitro.
  Nagao M, Sato T, Akimoto N, Kato Y, Takahashi M, Ito A.Exp Dermatol. 2009 Aug;18(8):730-3. doi: 10.1111/j.1600-0625.2008.00831.x. Epub 2009 Feb 18.
• 18. A water-soluble extract from Grifola frondosa, maitake mushroom, decreases lipid droplets in brown adipocyte tissue cells.
  Minamino K, Nagasawa Y, Ohtsuru M.J Nutr Sci Vitaminol (Tokyo). 2008 Dec;54(6):497-500.
• 19. Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy.
  Konno S.Int J Gen Med. 2009 Jul 30;2:91-108.
• 20. Possible disease remission in patient with invasive bladder cancer with D-fraction regimen.
  Rajamahanty S, Louie B, O’Neill C, Choudhury M, Konno S.Int J Gen Med. 2009 Jul 30;2:15-7.

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