Standard Herbal Extract

Ocimum Sanctum Extract Safety Tips

Handling of Ocimum Sanctum Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats.
  Han SY, Li HX, Ma X, Zhang K, Ma ZZ, Tu PF.J Ethnopharmacol. 2012 Dec 10. doi:pii: S0378-8741(12)00813-6.  10.1016/j.jep.2012.11.036. [Epub ahead of print]
• 2. [Study on optimization method of dynamic extraction process].
  Wang D, Zhang J, Zhang L, Wang Y, Liu A.Zhongguo Zhong Yao Za Zhi. 2012 May;37(10):1388-91. Chinese.
• 3. More accurate matrix-matched quantification using the standard superposition method for herbal medicines.
  Liu Y, Shi XW, Liu EH, Sheng LS, Qi LW, Li P.J Chromatogr A. 2012 Sep 7;1254:43-50. doi: 10.1016/j.chroma.2012.07.020. Epub 2012 Jul 13.
• 4. [Effect of notoginseng extracts and its components on lipopolysaccharide and galactosamine mixture-induced impaired hepatic function in mice].
  Komatsu K, Tanaka H, Nakagawa D, Kawashima K.Yakugaku Zasshi. 2012;132(7):831-6. Japanese.
• 5. Sesquiterpenes and cyclopeptides from the endophytic fungus Trichoderma asperellum SAMUELS, LIECKF. & NIRENBERG.
  Ding G, Chen AJ, Lan J, Zhang H, Chen X, Liu X, Zou Z.Chem Biodivers. 2012 Jun;9(6):1205-12. doi: 10.1002/cbdv.201100185.
• 6. Pharmacokinetic comparisons of single herb extract of Fufang Danshen preparation with different combinations of its constituent herbs in rats.
  Yang S, Zhang K, Lin X, Miao Y, Meng L, Chen W, Tang X.J Pharm Biomed Anal. 2012 Aug-Sep;67-68:77-85. doi: 10.1016/j.jpba.2012.03.058. Epub 2012 Apr 10.
• 7. Effects of Panax notoginseng flower extract on the TGF-β/Smad signal             transduction pathway in heart remodeling of human chymase transgenic mice.
  Wang Y, Qian P, Liu P, Wei L, Cao M, Zhou L, Zhou D, Lin ZX.Mol Med Report. 2012 Jun;5(6):1443-8. doi: 10.3892/mmr.2012.856. Epub 2012 Apr 2.
• 8. Analysis of Panax notoginseng metabolites in rat bile by liquid chromatography-quadrupole time-of-flight mass spectrometry with microdialysis sampling.
  Wen XD, Yang J, Ma RH, Gao W, Qi LW, Li P, Bauer BA, Du GJ, Zhang Z, Somogyi J, Wang CZ, Yuan CS.J Chromatogr B Analyt Technol Biomed Life Sci. 2012 May 1;895-896:162-8. doi: 10.1016/j.jchromb.2012.03.009. Epub 2012 Mar 15.
• 9. Interstitial granulomatous drug reaction to a Chinese herb extract.
  Du XF, Yin XP, Zhang GL, Shi HJ, Shao MH.Eur J Dermatol. 2012 May-Jun;22(3):419-20. doi: 10.1684/ejd.2012.1700. No abstract available.
• 10. Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.
  He NW, Zhao Y, Guo L, Shang J, Yang XB.J Med Food. 2012 Apr;15(4):350-9. doi: 10.1089/jmf.2011.1801. Epub 2012 Feb 8.
• 11. Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation.
  Pan C, Huo Y, An X, Singh G, Chen M, Yang Z, Pu J, Li J.Vascul Pharmacol. 2012 Mar-Apr;56(3-4):150-8. doi: 10.1016/j.vph.2011.12.006. Epub 2012 Jan 3.
• 12. [Effects of extracts from Panax ginseng, Panax notoginseng and Ligusticum chuanxiong on expression of β-galactosidase and signal pathway p16-cyclin D/CDK-Rb in vascular smooth muscle cells].
  Tao LL, Lei Y.Zhong Xi Yi Jie He Xue Bao. 2012 Jan;10(1):76-84. Chinese.
• 13. [Study on the dynamic model with supercritical CO2 fluid extracting the lipophilic components in Panax notoginseng].
  Duan XC, Wang YZ, Zhang JR, Luo H, Zhang H, Xia LZ.Zhong Yao Cai. 2011 Aug;34(8):1280-5. Chinese.
• 14. Inhibition of TLR ligand- and interferon gamma-induced murine microglial activation by Panax notoginseng.
  Beamer CA, Shepherd DM.J Neuroimmune Pharmacol. 2012 Jun;7(2):465-76. doi: 10.1007/s11481-011-9333-0. Epub 2011 Dec 21.
• 15. Panax notoginsenoside produces neuroprotective effects in rat model of acute spinal cord ischemia-reperfusion injury.
  Ning N, Dang X, Bai C, Zhang C, Wang K.J Ethnopharmacol. 2012 Jan 31;139(2):504-12. doi: 10.1016/j.jep.2011.11.040. Epub 2011 Dec 4.
• 16. Protective effects of Ligustrazine, Kakonein and Panax Notoginsenoside on the small intestine and immune organs of rats with severe acute pancreatitis.
  Zhang XP, Jiang J, Cheng QH, Ye Q, Li WJ, Zhu H, Shen JY.Hepatobiliary Pancreat Dis Int. 2011 Dec;10(6):632-7.
• 17. Target separation of a new anti-tumor saponin and metabolic profiling of leaves of Panax notoginseng by liquid chromatography with eletrospray ionization quadrupole time-of-flight mass spectrometry.
  Mao Q, Yang J, Cui XM, Li JJ, Qi YT, Zhang PH, Wang Q.J Pharm Biomed Anal. 2012 Feb 5;59:67-77. doi: 10.1016/j.jpba.2011.10.004. Epub 2011 Oct 13.
• 18. Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
  Wang ZJ, Song L, Guo LC, Yin M, Sun YN.Yakugaku Zasshi. 2011;131(6):993-1000.
• 19. Panax notoginseng Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice.
  Tsai KD, Yang SM, Lee JC, Wong HY, Shih CM, Lin TH, Tseng MJ, Chen W.Evid Based Complement Alternat Med. 2011;2011:404761. doi: 10.1155/2011/404761. Epub 2011 Mar 6.
• 20. Isolation of four high-purity dammarane saponins from extract of Panax notoginseng by centrifugal partition chromatography coupled with evaporative light scattering detection in one operation.
  Wang J, Liu CM, Li L, Bai HL.Phytochem Anal. 2011 May-Jun;22(3):263-7. doi: 10.1002/pca.1274. Epub 2011 Jan 24.