Standard Herbal Extract

Perilla Leaf Extract Safety Tips

Handling of Perilla Leaf Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. In vitro and in vivo activities of Peganum harmala extract against Leishmania major.
  Rahimi-Moghaddam P, Ebrahimi SA, Ourmazdi H, Selseleh M, Karjalian M, Haj-Hassani G, Alimohammadian MH, Mahmoudian M, Shafiei M.J Res Med Sci. 2011 Aug;16(8):1032-9.
• 2. Antibacterial activity in spices and local medicinal plants against clinical isolates of Karachi, Pakistan.
  Ali NH, Faizi S, Kazmi SU.Pharm Biol. 2011 Aug;49(8):833-9. doi: 10.3109/13880209.2010.551136. Epub 2011 Apr 18.
• 3. Screening of medicinal plants from Iranian traditional medicine for acetylcholinesterase inhibition.
  Adhami HR, Farsam H, Krenn L.Phytother Res. 2011 Aug;25(8):1148-52. doi: 10.1002/ptr.3409. Epub 2011 Feb 2.
• 4. Antibacterial and antifungal activities of (beta)-carboline alkaloids of Peganum harmala (L) seeds and their combination effects.
  Nenaah G.Fitoterapia. 2010 Oct;81(7):779-82. doi: 10.1016/j.fitote.2010.04.004. Epub 2010 Apr 14.
• 5. Effects of Peganum harmala (Zygophyllaceae) seed extract on the olive fruit fly (Diptera: Tephritidae) and its larval parasitoid Psyttalia concolor (Hymenoptera: Braconidae).
  Rehman JU, Wang XG, Johnson MW, Daane KM, Jilani G, Khan MA, Zalom FG.J Econ Entomol. 2009 Dec;102(6):2233-40.
• 6. Preliminary studies on the hypoglycemic effect of Peganum harmala L. Seeds ethanol extract on normal and streptozotocin induced diabetic rats.
  Singh AB, Chaturvedi JP, Narender T, Srivastava AK.Indian J Clin Biochem. 2008 Oct;23(4):391-3. doi: 10.1007/s12291-008-0086-3. Epub 2008 Dec 20.
• 7. A case of beta-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract.
  Frison G, Favretto D, Zancanaro F, Fazzin G, Ferrara SD.Forensic Sci Int. 2008 Aug 6;179(2-3):e37-43. doi: 10.1016/j.forsciint.2008.05.003. Epub 2008 Jul 7.
• 8. Peganum harmala can minimize Escherichia coli infection in poultry, but long-term feeding may induce side effects.
  Arshad N, Neubauer C, Hasnain S, Hess M.Poult Sci. 2008 Feb;87(2):240-9. doi: 10.3382/ps.2007-00341.
• 9. Evaluation of the analgesic effect of alkaloid extract of Peganum harmala L.: possible mechanisms involved.
  Farouk L, Laroubi A, Aboufatima R, Benharref A, Chait A.J Ethnopharmacol. 2008 Feb 12;115(3):449-54. Epub 2007 Oct 22.
• 10. Protective effects of Peganum harmala L. extract, harmine and harmaline against human low-density lipoprotein oxidation.
  Berrougui H, Isabelle M, Cloutier M, Hmamouchi M, Khalil A.J Pharm Pharmacol. 2006 Jul;58(7):967-74.
• 11. Antimicrobial activity and main chemical composition of two smoke condensates from Peganum harmala seeds.
  Shahverdi AR, Monsef-Esfahani HR, Nickavar B, Bitarafan L, Khodaee S, Khoshakhlagh N.Z Naturforsch C. 2005 Sep-Oct;60(9-10):707-10.
• 12. Xanthomicrol is the main cytotoxic component of Dracocephalum kotschyii and a potential anti-cancer agent.
  Jahaniani F, Ebrahimi SA, Rahbar-Roshandel N, Mahmoudian M.Phytochemistry. 2005 Jul;66(13):1581-92.
• 13. Antinociceptive effects of Peganum harmala L. alkaloid extract on mouse formalin test.
  Monsef HR, Ghobadi A, Iranshahi M, Abdollahi M.J Pharm Pharm Sci. 2004 Feb 19;7(1):65-9.
• 14. Relaxant activity of methanolic extract from seeds of Peganum harmala on isolated rat aorta.
  Berrougui H, Herrera-Gonzalez MD, Marhuenda E, Ettaib A, Hmamouchi M.Therapie. 2002 May-Jun;57(3):236-41.
• 15. Interaction of folk medicinal plant extracts with human alpha2-adrenoceptor subtypes.
  Saleem A, Engström M, Wurster S, Savola JM, Pihlaja K.Z Naturforsch C. 2002 Mar-Apr;57(3-4):332-8.
• 16. An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids.
  Sobhani AM, Ebrahimi SA, Mahmoudian M.J Pharm Pharm Sci. 2002 Jan-Apr;5(1):19-23.
• 17. Experimental toxicity of Peganum harmala seeds.
  Lamchouri F, Settaf A, Cherrah Y, El Hamidi M, Tligui N, Lyoussi B, Hassar M.Ann Pharm Fr. 2002 Mar;60(2):123-9.
• 18. In vitro cell-toxicity of Peganum harmala alkaloids on cancerous cell-lines.
  Lamchouri F, Settaf A, Cherrah Y, Hassar M, Zemzami M, Atif N, Nadori EB, Zaid A, Lyoussi B.Fitoterapia. 2000 Feb;71(1):50-4.
• 19. Effect of Peganum harmala extract on root tips of Allium cepa.
  Abderrahman SM.Cytobios. 1997;90(362-363):171-4.
• 20. Hypothermic effect of harmala alkaloid in rats: involvement of serotonergic mechanism.
  Abdel-Fattah AF, Matsumoto K, Gammaz HA, Watanabe H.Pharmacol Biochem Behav. 1995 Oct;52(2):421-6.

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