Standard Herbal Extract

Pumpkin Seed Extract Safety Tips

Handling of Pumpkin Seed Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Studies on the bioactivity of aqueous extract of pu-erh tea and its fractions: In vitro antioxidant activity and α-glycosidase inhibitory property, and their effect on postprandial hyperglycemia in diabetic mice.
  Huang Q, Chen S, Chen H, Wang Y, Wang Y, Hochstetter D, Xu P.Food Chem Toxicol. 2012 Dec 2. doi:pii: S0278-6915(12)00846-0.  10.1016/j.fct.2012.11.039. [Epub ahead of print]
• 2. Antioxidant Phenolic Compounds from Pu-erh Tea.
  Zhang HM, Wang CF, Shen SM, Wang GL, Liu P, Liu ZM, Wang YY, Du SS, Liu ZL, Deng ZW.Molecules. 2012 Nov 27;17(12):14037-45. doi: 10.3390/molecules171214037.
• 3. Hypoglycemic Effect of the Water Extract of Pu-erh Tea.
  Du WH, Peng SM, Liu ZH, Shi L, Tan LF, Zou XQ.J Agric Food Chem. 2012 Oct 1. [Epub ahead of print]
• 4. Evaluation of oral subchronic toxicity of Pu-erh green tea (camellia sinensis var. assamica) extract in Sprague Dawley rats.
  Wang D, Meng J, Xu K, Xiao R, Xu M, Liu Y, Zhao Y, Yao P, Yan H, Liu L.J Ethnopharmacol. 2012 Aug 1;142(3):836-44. doi: 10.1016/j.jep.2012.06.011. Epub 2012 Jun 16.
• 5. Antiobesity effects of Chinese black tea (Pu-erh tea) extract and gallic acid.
  Oi Y, Hou IC, Fujita H, Yazawa K.Phytother Res. 2012 Apr;26(4):475-81. doi: 10.1002/ptr.3602. Epub 2011 Aug 16.
• 6. Investigation of antiradical potential of different kinds of teas and extracts from these teas using antiradical activity units (TAU).
  Wojciechowski D, Sroka Z, Gamian A.Postepy Hig Med Dosw (Online). 2011 Nov 30;65:796-803.
• 7. Pu-erh tea, green tea, and black tea suppresses hyperlipidemia, hyperleptinemia and fatty acid synthase through activating AMPK in rats fed a high-fructose diet.
  Huang HC, Lin JK.Food Funct. 2012 Feb;3(2):170-7. doi: 10.1039/c1fo10157a. Epub 2011 Nov 30.
• 8. Pu-erh black tea extract supplementation attenuates the oxidative DNA damage and oxidative stress in Sprague-Dawley rats with renal dysfunction induced by subchronic 3-methyl-2-quinoxalin benzenevinylketo-1,4-dioxide exposure.
  Wang D, Luo X, Zhong Y, Yang W, Xu M, Liu Y, Meng J, Yao P, Yan H, Liu L.Food Chem Toxicol. 2012 Feb;50(2):147-54. doi: 10.1016/j.fct.2011.10.069. Epub 2011 Nov 3.
• 9. Antibacterial property and mechanism of a novel Pu-erh tea nanofibrous membrane.
  Su Y, Zhang C, Wang Y, Li P.Appl Microbiol Biotechnol. 2012 Feb;93(4):1663-71. doi: 10.1007/s00253-011-3501-2. Epub 2011 Aug 20.
• 10. Improvements of mean body mass index and body weight in preobese and overweight Japanese adults with black Chinese tea (Pu-Erh) water extract.
  Kubota K, Sumi S, Tojo H, Sumi-Inoue Y, I-Chin H, Oi Y, Fujita H, Urata H.Nutr Res. 2011 Jun;31(6):421-8. doi: 10.1016/j.nutres.2011.05.004. Epub 2011 Jun 17. Erratum in: Nutr Res. 2012 Jun;32(6):470.
• 11. Changes of constituents and activity to apoptosis and cell cycle during fermentation of tea.
  Zhao H, Zhang M, Zhao L, Ge YK, Sheng J, Shi W.Int J Mol Sci. 2011;12(3):1862-75. doi: 10.3390/ijms12031862. Epub 2011 Mar 10.
• 12. Acute and subchronic oral toxicities of Pu-erh black tea extract in Sprague-Dawley rats.
  Wang D, Xu K, Zhong Y, Luo X, Xiao R, Hou Y, Bao W, Yang W, Yan H, Yao P, Liu L.J Ethnopharmacol. 2011 Mar 8;134(1):156-64. doi: 10.1016/j.jep.2010.11.068. Epub 2010 Dec 4.
• 13. Pu-erh black tea supplementation decreases quinocetone-induced ROS generation and oxidative DNA damage in Balb/c mice.
  Wang D, Zhong Y, Luo X, Wu S, Xiao R, Bao W, Yang W, Yan H, Yao P, Liu L.Food Chem Toxicol. 2011 Feb;49(2):477-84. doi: 10.1016/j.fct.2010.11.028. Epub 2010 Nov 26.
• 14. Effect of pu-erh tea on body fat and lipid profiles in rats with diet-induced obesity.
  Cao ZH, Gu DH, Lin QY, Xu ZQ, Huang QC, Rao H, Liu EW, Jia JJ, Ge CR.Phytother Res. 2011 Feb;25(2):234-8. doi: 10.1002/ptr.3247.
• 15. Enhancement of fermentation process in Pu-erh tea by tea-leaf extract.
  Hou CW, Jeng KC, Chen YS.J Food Sci. 2010 Jan-Feb;75(1):H44-8. doi: 10.1111/j.1750-3841.2009.01441.x.
• 16. Comparative safety evaluation of Chinese Pu-erh green tea extract and Pu-erh black tea extract in Wistar rats.
  Wang D, Xiao R, Hu X, Xu K, Hou Y, Zhong Y, Meng J, Fan B, Liu L.J Agric Food Chem. 2010 Jan 27;58(2):1350-8. doi: 10.1021/jf902171h.
• 17. Pu-erh tea attenuates hyperlipogenesis and induces hepatoma cells growth arrest through activating AMP-activated protein kinase (AMPK) in human HepG2 cells.
  Way TD, Lin HY, Kuo DH, Tsai SJ, Shieh JC, Wu JC, Lee MR, Lin JK.J Agric Food Chem. 2009 Jun 24;57(12):5257-64. doi: 10.1021/jf900730e.
• 18. Pu-erh tea aqueous extracts lower atherosclerotic risk factors in a rat hyperlipidemia model.
  Hou Y, Shao W, Xiao R, Xu K, Ma Z, Johnstone BH, Du Y.Exp Gerontol. 2009 Jun-Jul;44(6-7):434-9. doi: 10.1016/j.exger.2009.03.007. Epub 2009 Apr 5.
• 19. Efficient procedure for isolating methylated catechins from green tea and effective simultaneous analysis of ten catechins, three purine alkaloids, and gallic acid in tea by high-performance liquid chromatography with diode array detection.
  Hu B, Wang L, Zhou B, Zhang X, Sun Y, Ye H, Zhao L, Hu Q, Wang G, Zeng X.J Chromatogr A. 2009 Apr 10;1216(15):3223-31. doi: 10.1016/j.chroma.2009.02.020. Epub 2009 Feb 13.
• 20. Simultaneous determination of catechins, caffeine and gallic acids in green, Oolong, black and pu-erh teas using HPLC with a photodiode array detector.
  Zuo Y, Chen H, Deng Y.Talanta. 2002 May 16;57(2):307-16.

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