Standard Herbal Extract

Rabdosia Japonica Hara Extract Safety Tips

Handling of Rabdosia Japonica Hara Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Cytotoxicity of herbal extracts used for treatment of prostatic disease on head and neck carcinoma cell lines and non-malignant primary mucosal cells.
  Schmidt M, Polednik C, Roller J, Hagen R.Oncol Rep. 2013 Feb;29(2):628-36. doi: 10.3892/or.2012.2145. Epub 2012 Nov 19.
• 2. Benign prostatic hyperplasia and male lower urinary tract symptoms (LUTS).
  McNicholas T, Kirby R.Clin Evid (Online). 2011 Aug 26;2011. doi:pii: 1801.
• 3. The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth.
  Roell D, Baniahmad A.Mol Cell Endocrinol. 2011 Jan 30;332(1-2):1-8. doi: 10.1016/j.mce.2010.09.013. Epub 2010 Oct 19. Review.
• 4. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies.
  Mantovani F.Minerva Urol Nefrol. 2010 Dec;62(4):335-40.
• 5. Diagnosis and management of benign prostatic hyperplasia.
  Edwards JL.Am Fam Physician. 2008 May 15;77(10):1403-10. Review.
• 6. Phytosterol Pygeum africanum regulates prostate cancer in vitro and in vivo.
  Shenouda NS, Sakla MS, Newton LG, Besch-Williford C, Greenberg NM, MacDonald RS, Lubahn DB.Endocrine. 2007 Feb;31(1):72-81.
• 7. A critical review of the pharmacology of the plant extract of Pygeum africanum in the treatment of LUTS.
  Edgar AD, Levin R, Constantinou CE, Denis L.Neurourol Urodyn. 2007;26(4):458-63; discussion 464. Review.
• 8. Pygeum africanum extract inhibits proliferation of human cultured prostatic fibroblasts and myofibroblasts.
  Boulbès D, Soustelle L, Costa P, Haddoum M, Bali JP, Hollande F, Magous R.BJU Int. 2006 Nov;98(5):1106-13.
• 9. Extracts from Pygeum africanum and other ethnobotanical species with antiandrogenic activity.
  Schleich S, Papaioannou M, Baniahmad A, Matusch R.Planta Med. 2006 Jul;72(9):807-13. Epub 2006 Jun 19.
• 10. Activity-guided isolation of an antiandrogenic compound of Pygeum africanum.
  Schleich S, Papaioannou M, Baniahmad A, Matusch R.Planta Med. 2006 May;72(6):547-51.
• 11. [Tadenan (Pygeum africanum extract) in the treatment of patients with benign prostatic hyperplasia].
  [No authors listed]Urologiia. 2004 Sep-Oct;(5):70-2. Review. Russian.  No abstract available.
• 12. Is there a scientific basis for the therapeutic effects of serenoa repens in benign prostatic hyperplasia? Mechanisms of action.
  Buck AC.J Urol. 2004 Nov;172(5 Pt 1):1792-9. Review.
• 13. The African cherry (Prunus africana): can lessons be learned from an over-exploited medicinal tree
  Stewart KM.J Ethnopharmacol. 2003 Nov;89(1):3-13. Review.
• 14. Toxicity of chloroform extract of prunus africana stem bark in rats: gross and histological lesions.
  Gathumbi PK, Mwangi JW, Mugera GM, Njiro SM.Phytother Res. 2002 May;16(3):244-7.
• 15. The role of phytotherapy in treating lower urinary tract symptoms and benign prostatic hyperplasia.
  Dreikorn K.World J Urol. 2002 Apr;19(6):426-35. Review.
• 16. Identification of components of Prunus africana extract that inhibit lipid peroxidation.
  Hass MA, Nowak DM, Leonova E, Levin RM, Longhurst PA.Phytomedicine. 1999 Nov;6(5):379-88.
• 17. Effect of oral Tadenan treatment on rabbit bladder structure and function after partial outlet obstruction.
  Levin RM, Hass MA, Bellamy F, Horan P, Whitbeck K, Chow PH, Kung LS, Gosling J.J Urol. 2002 May;167(5):2253-9.
• 18. Pygeum africanum for benign prostatic hyperplasia.
  Wilt T, Ishani A, Mac Donald R, Rutks I, Stark G.Cochrane Database Syst Rev. 2002;(1):CD001044. Review.
• 19. The effect of Pygeum africanum on fibroblast growth factor (FGF) and transforming growth factor beta (TGF beta 1/LAP) expression in animal model.
  Szolnoki E, Reichart E, Marchal S, Szegedi G.Acta Microbiol Immunol Hung. 2001;48(1):1-9.
• 20. Effects of Pygeum africanum extract (Tadenan) on vasoactive intestinal peptide receptors, G proteins, and adenylyl cyclase in rat ventral prostate.
  Solano RM, García-Fernández MO, Clemente C, Querol M, Bellamy F, Sanchez-Chapado M, Prieto JC, Carmena MJ.Prostate. 2000 Nov 1;45(3):245-52.

Details