Best Herbal Extracts

Botanical Ingredient

Sanguinarine

Sanguinarine is extracted from Macleaya cordata (Willd.) R. Br.. Stanford Chemicals has been providing quality Sanguinarine and many other natural plant extracts for over 25 years.

SKU HE3111 Category

Sanguinarine Safety Tips

Handling of Sanguinarine should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

  • 1. Screening of differentially expressed genes and small molecule drugs of pediatric allergic asthma with DNA microarray.
    Wang XQ, Wang XM, Zhou TF, Dong LQ.Eur Rev Med Pharmacol Sci. 2012 Dec;16(14):1961-6.
  • 2. Synthesis of 2-Aryl-3,4-dihydroisoquinolin-2-ium Bromides and Their in vitro Acaricidal Activity against Psoroptes cuniculi.
    Ma YN, Yang XJ, Pan L, Hou Z, Geng HL, Song XP, Zhou L, Miao F.Chem Pharm Bull (Tokyo). 2012 Dec 5. [Epub ahead of print]
  • 3. DNA abasic site-selective enhancement of sanguinarine fluorescence with a large emission shift.
    Wu F, Sun Y, Shao Y, Xu S, Liu G, Peng J, Liu L.PLoS One. 2012;7(11):e48251. doi: 10.1371/journal.pone.0048251. Epub 2012 Nov 20.
  • 4. Association of Mustard Oil as Cooking Media with Carcinoma of the Gallbladder.
    Dixit R, Srivastava P, Basu S, Srivastava P, Mishra PK, Shukla VK.J Gastrointest Cancer. 2012 Nov 23. [Epub ahead of print]
  • 5. Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells.
    Eid SY, El-Readi MZ, Wink M.Phytomedicine. 2012 Nov 15;19(14):1288-97. doi: 10.1016/j.phymed.2012.08.010. Epub 2012 Nov 10.
  • 6. 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents.
    Kelley C, Zhang Y, Parhi A, Kaul M, Pilch DS, Lavoie EJ.Bioorg Med Chem. 2012 Dec 15;20(24):7012-29. doi: 10.1016/j.bmc.2012.10.009. Epub 2012 Oct 17.
  • 7. In Vitro Antifungal Activity of Sanguinarine and Chelerythrine Derivatives against Phytopathogenic Fungi.
    Yang XJ, Miao F, Yao Y, Cao FJ, Yang R, Ma YN, Qin BF, Zhou L.Molecules. 2012 Nov 2;17(11):13026-35. doi: 10.3390/molecules171113026.
  • 8. Characterization of a flavoprotein oxidase from opium poppy catalyzing the final steps in sanguinarine and papaverine biosynthesis.
    Hagel JM, Beaudoin GA, Fossati E, Ekins A, Martin VJ, Facchini PJ.J Biol Chem. 2012 Dec 14;287(51):42972-83. doi: 10.1074/jbc.M112.420414. Epub 2012 Nov 1.
  • 9. Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives.
    Parhi A, Kelley C, Kaul M, Pilch DS, Lavoie EJ.Bioorg Med Chem Lett. 2012 Dec 1;22(23):7080-3. doi: 10.1016/j.bmcl.2012.09.097. Epub 2012 Oct 2.
  • 10. Digitonin synergistically enhances the cytotoxicity of plant secondary metabolites in cancer cells.
    Eid SY, El-Readi MZ, Wink M.Phytomedicine. 2012 Nov 15;19(14):1307-14. doi: 10.1016/j.phymed.2012.09.002. Epub 2012 Oct 11.
  • 11. Structural Modification of Sanguinarine and Chelerythrine and Their in Vitro Acaricidal Activity against Psoroptes cuniculi.
    Miao F, Yang XJ, Ma YN, Zheng F, Song XP, Zhou L.Chem Pharm Bull (Tokyo). 2012 Dec 1;60(12):1508-13. Epub 2012 Sep 21.
  • 12. Biochemical genomics for gene discovery in benzylisoquinoline alkaloid biosynthesis in opium poppy and related species.
    Dang TT, Onoyovwi A, Farrow SC, Facchini PJ.Methods Enzymol. 2012;515:231-66. doi: 10.1016/B978-0-12-394290-6.00011-2.
  • 13. Alkaloids isolated from natural herbs as anticancer agents.
    Lu JJ, Bao JL, Chen XP, Huang M, Wang YT.Evid Based Complement Alternat Med. 2012;2012:485042. doi: 10.1155/2012/485042. Epub 2012 Sep 4.
  • 14. Sanguinarine inhibits the growth of human cervical cancer cells through the induction of apoptosis.
    Xu JY, Meng QH, Chong Y, Jiao Y, Zhao L, Rosen EM, Fan S.Oncol Rep. 2012 Dec;28(6):2264-70. doi: 10.3892/or.2012.2024. Epub 2012 Sep 11.
  • 15. The anti-inflammatory effects of sanguinarine and its modulation of inflammatory mediators from peritoneal macrophages.
    Niu X, Fan T, Li W, Xing W, Huang H.Eur J Pharmacol. 2012 Aug 15;689(1-3):262-9. doi: 10.1016/j.ejphar.2012.05.039. Epub 2012 Jun 13.
  • 16. Molecular basis for differential glycine transporters sensitivity to sanguinarine.
    Jursky F, Baliova M, Mihalikova A.Toxicol Lett. 2012 Aug 3;212(3):262-7. doi: 10.1016/j.toxlet.2012.06.004. Epub 2012 Jun 13.
  • 17. Binding of the anticancer alkaloid sanguinarine with tRNA(phe): spectroscopic and calorimetric studies.
    Hossain M, Kabir A, Suresh Kumar G.J Biomol Struct Dyn. 2012;30(2):223-34. doi: 10.1080/07391102.2012.677774.
  • 18. Luminescence and binding properties of two isoquinoline alkaloids chelerythrine and sanguinarine with ctDNA.
    Li J, Li B, Wu Y, Shuang S, Dong C, Choi MM.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Sep;95:80-5. doi: 10.1016/j.saa.2012.04.075. Epub 2012 Apr 28.
  • 19. Establishment of a sanguinarine-producing cell suspension culture of Argemone mexicana L (Papaveraceae): induction of alkaloid accumulation.
    Vázquez-Flota FA, Monforte-González M, Guízar-González C, Rubio-Piña J, Trujillo-Villanueva K.Methods Mol Biol. 2012;877:271-6. doi: 10.1007/978-1-61779-818-4_21.
  • 20. A model for cardiomyocyte cell death: Insights into mechanisms of oncosis.
    Weerasinghe P, Hallock S, Brown RE, Loose DS, Buja LM.Exp Mol Pathol. 2012 May 16. [Epub ahead of print]

Details

Product Name

Sanguinarine

CAS No.

2447-54-3

Molecular Formula

C20H14N04

Molecular Weight

332.33

Botanical Source

Macleaya cordata (Willd.) R. Br.

Purity

98% HPLC

Appearance

Yellow powder

Package

25 kg/drum

Storage

Stored in cool & dry places, protected from direct sunlight and heat.










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