Botanical Ingredient

Yohimbine Safety Tips

Handling of Yohimbine should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

• 1. Tonic Modulatory Role of Mouse Cerebellar α- and β-Adrenergic receptors in the Expression of Ethanol-Induced Ataxia: Role of AC-cAMP.
  Dar MS, Al-Rejaie S.Behav Brain Res. 2012 Dec 11. doi:pii: S0166-4328(12)00780-2.  10.1016/j.bbr.2012.12.006. [Epub ahead of print]
• 2. An investigation about the inhibition of acute ischemia/reperfusion damage by dexmedetomidine in rat ovarian tissue.
  Kurt A, Ingec M, Isaoglu U, Yilmaz M, Cetin N, Calik M, Polat B, Akcay F, Gundogdu C, Suleyman H.Gynecol Endocrinol. 2012 Dec 11. [Epub ahead of print]
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• 4. Determination of Indole Alkaloids and Highly Volatile Compounds in Rauvolfia verticillata by HPLC-UV and GC-MS.
  Hong B, Li W, Song A, Zhao C.J Chromatogr Sci. 2012 Dec 4. [Epub ahead of print]
• 5. Antinociceptive Effect of Lupeol: Evidence for a Role of Cytokines Inhibition.
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• 6. Ethopharmacological evaluation of the rat exposure test: A prey-predator interaction test.
  Campos KF, Amaral VC, Rico JL, Miguel TT, Nunes-de-Souza RL.Behav Brain Res. 2012 Nov 27. doi:pii: S0166-4328(12)00745-0.  10.1016/j.bbr.2012.11.023. [Epub ahead of print]
• 7. Venlafaxine and Neuropathic Pain.
  Cegielska-Perun K, Bujalska-Zadro?ny M, Tatarkiewicz J, G?sinska E, Makulska-Nowak HE.Pharmacology. 2012 Nov 22;91(1-2):69-76. [Epub ahead of print]
• 8. The antidiarrhoeal activity of the aqueous root extract of Aristolochia ringens (Vahl.) Aristolochiaceae.
  Adeyemi OO, Aigbe FR, Badru OA.Nig Q J Hosp Med. 2012 Jan-Mar;22(1):29-33.
• 9. Inhibition of insulin secretion from rat pancreatic islets by dexmedetomidine and medetomidine, two sedatives frequently used in clinical settings.
  Yamato-Kodera S, Yoshida M, Dezaki K, Yada T, Murayama T, Kawakami M, Kakei M.Endocr J. 2012 Nov 22. [Epub ahead of print]
• 10. Plasma Norepinephrine in Hypertensive Rats Reflects α(2)-Adrenoceptor Release Control Only When Re-Uptake is Inhibited.
  Berg T, Walaas SI, Roberg BÅ, Huynh TT, Jensen J.Front Neurol. 2012;3:160. doi: 10.3389/fneur.2012.00160. Epub 2012 Nov 8.
• 11. Yohimbine increases opioid-seeking behavior in heroin-dependent, buprenorphine-maintained individuals.
  Greenwald MK, Lundahl LH, Steinmiller CL.Psychopharmacology (Berl). 2012 Nov 17. [Epub ahead of print]
• 12. [Effect of alpha2-adrenergic receptor antagonist yohimbine on thermoregulatory responses to cooling].
  Kozyreva TV, Tkachenko EIa, Gonsales EV.Ross Fiziol Zh Im I M Sechenova. 2012 Aug;98(8):1008-15. Russian.
• 13. The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model.
  Stepanovic-Petrovic RM, Micov AM, Tomic MA, Ugresic ND.Anesth Analg. 2012 Dec;115(6):1457-66. doi: 10.1213/ANE.0b013e31826c7fc2. Epub 2012 Nov 9.
• 14. Molecular cloning and pharmacological characterisation of a tyramine receptor from the rice stem borer, Chilo suppressalis (Walker).
  Wu SF, Huang J, Ye GY.Pest Manag Sci. 2013 Jan;69(1):126-34. doi: 10.1002/ps.3378. Epub 2012 Nov 5.
• 15. Role of the Cholecystokinin System in Anxiolytic Activity of Dipeptide GB-115.
  Kolik LG, Gudasheva TA, Seredenin SB.Bull Exp Biol Med. 2012 Oct;153(6):851-4. English, Russian.
• 16. Alterations in ethanol seeking and self-administration following yohimbine in selectively bred alcohol-preferring (P) and high alcohol drinking (HAD-2) rats.
  Bertholomey ML, Verplaetse TL, Czachowski CL.Behav Brain Res. 2013 Feb 1;238:252-8. doi: 10.1016/j.bbr.2012.10.030. Epub 2012 Oct 26.
• 17. Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms.
  Devrim Can O, Demir Özkay U, Irfan Üçel U.Eur J Pharmacol. 2012 Oct 23. doi:pii: S0014-2999(12)00863-1.  10.1016/j.ejphar.2012.10.017. [Epub ahead of print]
• 18. Noradrenergic Control of Neuronal Firing in Cerebellar Nuclei: Modulation of GABA Responses.
  Di Mauro M, Li Volsi G, Licata F.Cerebellum. 2012 Oct 18. [Epub ahead of print]
• 19. Ankle Joint Mobilization Affects Postoperative Pain Through Peripheral and Central Adenosine A1 Receptors.
  Martins DF, Mazzardo-Martins L, Cidral-Filho FJ, Santos AR, Stramosk J.Phys Ther. 2012 Oct 19. [Epub ahead of print]
• 20. Olfactory bulb α2-adrenoceptor activation promotes rat pup odor-preference learning via a cAMP-independent mechanism.
  Shakhawat AM, Harley CW, Yuan Q.Learn Mem. 2012 Oct 15;19(11):499-502. doi: 10.1101/lm.027359.112.

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